Rational use of antiparasitic drugs

Question 1

Hvad er Metaphylactic?

Answer 1

allowed to treat if a recurrent problem at herd level can

be proven e.g. toltrazuril for piglets; IR-bolus

Question 2

Hvad giver man mod Fasciaola Hepatica ?

Answer 2

Triclabendazol ?

Question 3

Hvad virker mod H. contortus ?

Answer 3

Closantel

Question 4

Hvad giver man til lakterende kvæg

Answer 4

Eprinomectin

Question 5

Hvad er cut-off for anthelmintika brug, EPG (ved hest ?)

Answer 5

221 EPG

Question 6

Nævn nogen faktorer som disponerer for AR

Answer 6

• hyppige behandlinger
  * for lav dosis
  * vedvarende brug af samme gruppe/sustained release drugs
  * lille refugium ved behandling eks. dose-and-move; “foreffektive”
  behandlinger, suppressive treatment
  * helminther med kort generationsinterval

Question 7

Forklar Refugium

Answer 7

the proportion of a given parasite population thatescapes exposure to drugs

Question 8

Generelle guidelines for brug af anthelmintika

Answer 8

Korrekt diagnose

smalt spektrum

INGEN under-dosering

Tjek effekten i ny og næ

Behandl kun dyr som har brug for behandling

Lav et regufium, ex. ved TST (Targeted selective treament)

Lad være med “dose and move” -Behandl 14 dage før de flyttes eller flyt dem, lad dem smitte arealet og behandl derefter (Dose and move giver resistens). DET SKAL VÆRE MOVE-AND-DOSE

Lad værre med at “køb” resistens ind i populationen

Bland ikke får og geder

Question 9

Forklar TST - targeted selective treatment

Answer 9

treat only:

clinically affected animals e.g. scouring or anaemia
FAMACHA

animal with high susceptibility e.g. lactating animals
animals with high egg excretion, thus major
contaminators
Horses: threshold 200 epg orS. vulgaris present

animals with poor weight gain

Question 10

Selecting the target. Hvilke parametre kigger du på?

Answer 10

High faecal egg counts

Performance/weight changes

Question 11

Hvilken parasit må gerne få profylaktisk behandling ?

Answer 11

Rævens dværgbændelorm

Question 12

Hvad gør man hvis der er påvist AR

Answer 12

• don’t continue using dewormers of the same drugclass
• yearly check on efficacy of used drug class (e.g.in vitro
tests)
• check faecal egg count to monitor infection and for
prediction of the “right time” to treat
• apply grazing management and optimise feeding
• strictly use of quarantine management

Question 13

HVad er IPC - Integrated Parasite Control ?

Answer 13

Basically, IPC islivestock management procedures and other
non-chemical approachesin combination withdrug usethat
aims at maintaining parasites at levels acceptablein terms of
livestock welfare and productivity

Question 14

anti-parasitic crops - nævn en afgrøde som har indvirkning på en parasit

Answer 14

Garvesyreholdige planter - condensed tannins.

Med virkning på H. contortus i geder.