Rate Limiting Enzymes Flashcards
1
Q
Glycogen synthase
A
Glycogen synthesis
Glycogen core UDP-glucose —> glycogen core linear unbranded a-1,4 linkage
2
Q
Glycogen phosphorylase
A
Glycogen degradation
Glycogen core —> glycogen core glu-1-P
3
Q
HMG CoA reductase
A
Cholesterol biosynthesis
Acetyl CoA —> mevalonate
4
Q
Isocitrate dehydrogenase
A
TCA
isocitrate —> alpha ketoglutarate
5
Q
Glucose-6-PDH
A
Pentose phosphate pathway
Glucose 6P —> 6-phosphogluconolactate
6
Q
7alpha hydroxylase
A
Bile salt synthesis
Cholesterol —> 7-alpha hydroxycholesterol
7
Q
HMG CoA synthetase
A
KB formation
Acetoacetyl coA —> HMG CoA