Ras Flashcards
1
Q
Ras
A
G protein
Signals to nucleus
Signal for proliferation
2
Q
Intrinsic_______________activity switches___________.
This activity is stimulated by____________.
A
GTPase
Protein off
Ras-GAPs
3
Q
Activated by______________ which exchange___________________.
A
GEFs
GTP for GDP
4
Q
Maintained in inactive state by_____________.
A
Guanine nucleotide dissociation inhibitors (GDI)
5
Q
Active when____________, inactive when_____________.
A
Bound to GTP
Bound to GDP
6
Q
Ras/GTP __________ the protein kinase ______ and _________ a kinase cascade signalling to the nucleus.
A
Activates
C-raf
Activates
