Random3 Flashcards
what two classes of meds SHORTEN NDMB
anticonvulsants (phenytoin, carbamazepine) cholinesterase inhibitors (neostigmine)
which beta blockers are non-specific?
after m
prophylaxis for dentist for heart patients
only consider procedures with gingival, bronch, skin manipulation
heart transpant with residual valvular abnormalities
previous IE
prosthetic valves
aspirin overdose symptoms
initially nonspecific - n/v/tinnitus
at first, hyperventilate -> stimulates medullary respiratory area. (resp alk) THEN metab acid
metabolic effects of respiratory alkalosis
hypoCa (H ions taken off albumin, which now sucks up Ca -> tingling), hypoK, hypophos)
Fick equation
SvO2 = SaO2 - [VO2 / (CO x Hgb x 1.36)]
VO2 = total body oxygen consumption
SO things that decrease SvO2
- MI = less CO
- decreased arterial oxygen saturation
- decrease o2 carrying capacity
- increased consumption (pain, shivering, hyperthermia)
what does the recurrent laryngeal nerve do?
abducts and adducts vocal cords. Provides motor function to all muscles of larynx EXCEPT cricothyroid. Sensation to larynx BELOW glottis. Comes from Vagus nerve
what does the superior laryngeal nerve, internal brnach do?
sensory above glottis
SIME = sensory internal, motor external
what does SLN, external branch do?
cricothyroid muscle, adducts VC
when is Succs contraindicated and why?
in patients >24 hours from burn, trauma, neuromuscular disorders, prolonged immobility 2/2 upregulation of extrajunctional nicotinic ACh receptors. Can raise K by 3.5 as opposed to 0.5 normally
also usually avoided in peds population
signs and symptoms of nitroprusside toxicity
AGMA, CNS depression, arrythmias, elevated mixed venous oxygenation
average stroke volume?
60-100ml/beat
how do we make the diagnosis of carbon monoxide poisoning?
co-oximetry (VBG/ABG)
elevated levels of COHgb (>15)
Tx: high FiO2
hyperbaric chamber only IF COhgb >30 or severe symptoms (obtunded, delirium, bradyarrythmias)
Fa/Fi - soluble agents - decreased CO or increased MV
both cause faster induction and rise of FA/FI
does HCO3- buffer H+?
NO! But it facilitates transport of H+ intracellularly where intracellular processes (proteins, phosphates, hgb) do actual buffering
why do liver patients have thrombocytopenia?
splenic sequestration and reduced thrombopoetin production by liver
platelet count can informally be used for progression of portal hypertension
why are factor 8 and vwf increased in liver disease?
produced in endothelium, NOT liver
why don’t liver patients spontaneously bleed?
increase in BOTH pro AND anticoagulant factors
low fibrinogen in a liver patient can indicate what?
DIC - fibrinogen is dysfunctional and usually INCREASED in liver patients.
power of a study
1-B
B is usually 10-20%
power = chance of correctly rejecting null hypothesis (no treatment effect) when alternative hypothesis is true
what measures the partial pressure of O2 requiring a voltage source?
clark electrode
sanz electrode is used to measure
pH of blood
severinghaus electrode is used to measure
Co2
based on the fact that pH and CO2 change in a linear fashion with temperature
all about doxorubicin
cardiomyopathy, pulm, hepatic, renal
dose-dependent
ekg used for acute toxicity monitoring
