Random SBAs Flashcards
What is Bupropion used for?
Smoking cessation and quitting
What cranial nerve has a nucleus in the pons?
Facial
What is the output fibre tact of the hippocampus called?
Fornix
What drug is an NMDA antagonist?
Phencyclidine (PCP)
What drug is used as a headache prophylaxis?
Methysergide
What is the function of Tiagabine?
GAT-1 inhibitor
What is the mechanism of phenobarbitone?
GABA modulator
What happened to HM after epilepsy surgery?
Couldn’t make new memories
Which of the following is an SSRI: Clomipramine Iproniazid Venlaflaxine Reboxetine Citalopram
Citalopram
What does Ondansetron target?
5-HT3 antagonist
What does Buspirone target?
5-HT1a agonist
What receptor must magnesium be removed from?
NMDA receptor
What type of injection is for slow release?
Intramuscular
What receptor is a type of cold nociceptor?
TRPM8
What is measured in the cold pressor test?
Intensity and tolerance
What is the main outflow tract of the cerebral peduncles?
Corticospinal
What type of cancer compresses the cerebellum?
Medullablastoma
What part of the brain has universal spread in depression?
Cerebral cortex
How long is a sleeping cycle?
90 minutes
Where is sleep initiated?
Hypothalamus (suprachiasmatic nucleus)
What wave is between 13-30 Hz?
Beta wave
What state has low awareness but high arousal?
Minimal conscious state
What are slow pain fibres?
C fibres
What enzyme synthesises prostaglandins?
COX-2
What is the leading cause of ischaemic stroke?
Atherosclerosis
What will an ACA stroke cause?
Ataxia
What can come before a migraine: Nausea + vomiting Tiredness + yawning Sensitivity to light/sound Diuresis Difficulty focusing
Tiredness + yawning
What is between the lateral ventricles and 3rd ventricle?
Interventricular foramen/foramen of Monro
Where is serotonin produced?
Raphe nucleus
What monoamine is associated with reward?
Dopamine
What does zolpidem target?
GABAa
What does marijuana target?
CB1 receptor
Which receptors is associated with paroxysmal depolarising shift in epilepsy?
NMDA
Which area of the brain is stimulated in DBS for Parkinson’s disease?
Subthalamic nucleus
Which nucleus in the basal ganglia is input to the thalamus?
GPi
Where are Purkinje cells found?
Purkinje/Molecular layer of the cerebellum
What is the term that describes when a non-noxious stimulus elicits a pain response?
Allodynia
Which of the following is a secondary headache: Cluster headache Trigeminal neuralgia Headache due to meningitis Hemicrania continua
Headache due to meningitis
Which of the following best describes a 5-HT3 receptor:
Ligand-gated
GPCR
They are coupled to inositol phospholipid turnover
Ligand-gated
45 y/o male collapses in a shopping centre whilst convulsing. The paramedics arrive 12 minutes later to find him still having a seizure. What is the acute treatment they administer: Lamotrigine Lorazepam Carbamazepine Vigabatrin Levetiracetam
Lorazepam
What is Naxolone?
Used in acute opioid overdose
highest affinity for u-opioid receptor; then delta; then kappa
Which NT is associated with promoting sleep: Dopamine Noradrenaline Melatonin Serotonin Histamine
Melatonin
Where does the superior peduncles of the cerebellum project to?
Thalamus