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Neurology > More random BB SBAs > Flashcards

More random BB SBAs Flashcards

1
Q

which receptor is associated with the paroxysmal depolarising shift in epilepsy?

A

NMDA

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2
Q

Which deep brain structure is stimulated DBS in Parkinson’s?

A

Subthalamic nucleus

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3
Q

Which of the following nucleus in the basal ganglia is input to the thalamus?

A

Glob pallidus internal

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4
Q

Where are the Purkinje cells found?

A

Molecular layer of the cerebral cortex

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5
Q

What is the term used to describe when a non-noxious stimulus elicits a pain response?

A

Allodynia

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6
Q

Which type of receptor is the 5-HT3 receptor?

A

Ligand-gated ion

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7
Q

45 y/o man collapses in a shopping centre while convulsing. The paramedics arrive 12 minutes later to find him still have a seizure. What is the acute treatment they administer?

A

Most likely IV diazepam

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8
Q

What is naloxone?

A

Opioid antagonist
Used to block/reverse the effects of opioid drugs (good to use in opioid overdose)
Has high affinity for mu opioid receptors

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9
Q

Which NTs promote sleep?

A

GABA
Melatonin
Adenosine

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10
Q

Where does the superior peduncles of the cerebellum project to?

A

Thalamus

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11
Q

What is long-term potentiation and depression?

A

To do with memory and learning see flashcard on memory and amnesia

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12
Q

What receptor does memantine act on?

A

NMDA

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13
Q

What increase the incidence of subdural haemorrhages, other than age?

A

Anticoagulants
Long-term alcohol abuse
Dementia
CSF leak

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14
Q

What area is overactive in OCD?

A

*Amygdala (according to notes)

Answers on google drive:
Orbital gyrus 
Head of caudate nucleus
Insula 
ACC

NOT:
Medial PFC
Posterior caudate

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15
Q

What other area/s of the brain is a target for DBS in Parkinson’s?

A

Zona incerta

Globus pallidus internal

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16
Q

What is tardive dyskinesia?

A

involuntary, repetitive body movements - may include grimacing, sticking out the tongue, or smacking the lips.

17
Q

Which drug has zero order?

A

Phenytoin

18
Q

What is the general mode of action of benzodiazepines?

A

Positive allosteric modulators of GABAa

19
Q

What receptor does sumatriptan bind to?

A

5HT1D/B

20
Q

What is methadone?

A

Opioid substitute

21
Q

What is the primary nucleus involved with cholinergic innervation of the cerebral cortex?

A

Nucleus Basalis of Meynert

22
Q

Waves of 13-20 Hz (high frequency) but with low amplitude are indicative of what state in a person?

A

Normal waking

23
Q

What is the most common causes of ischaemic stroke?

A

Thrombosis
Embolism
Systemic hypo perfusion (shock)
Cerebral venous sinus thrombosis

24
Q

What is the mechanism of action of ecstasy?

A

Presynaptic releasing agent of 5-HT, NA, DA

Acts on the trace-amine associated receptor 1 and vesicular monoamine transporter 2

25
Q

Give examples of SSRIs

A

Citalopram
Fluoxetine
Paroxetine
Sertraline

26
Q

Give examples of selective MAOb inhibitors

A

Rasagiline
Selegiline

Non-selective:
Phenelzine
Tranylcypromine
Iproniazid

27
Q

Which of the following drugs for schizophrenia is associated with agranulocytosis?

A

Clozapine

28
Q

In an outpatient department, testing of which cranial nerve reflex would be most appropriate? (idk if there wad a scenario for this, it doesn’t make much sense to me…)

A

Corneal
Cough
Gag
Pupillary light reflex

29
Q

following a major car accident, a man sustained multiple injuries…Upon arrival to the hospital, what is the first action taken in terms of management?

A

CT head
Resuscitation
Measure and management of ICP?

30
Q

Which of the following drugs is a DOPA decarboxylase inhibitor and CANNOT cross the BBB?

A

Carbidopa

31
Q

What brain structure comes after the hippocampus in the Paper memory circuit?

A

Mamillary body

32
Q

What do the plaques in AD contained?

A

Beta amyloid

33
Q

What receptor does marijuana bind to in the brain?

A

CB1

34
Q

Which enzyme is at the site of inflammation and makes compounds that sensitise nociceptors?

A

COX-2 at inflammatory tissues

35
Q

What fibres are involved in acupuncture?

A

A-delta

Neurology (46 decks)

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