Random Diseases I've never heard of Flashcards
Aspirin sensitive asthma
Asthma with nasal polyps
Avoid aspirin or NSAIDs because they can cause systemic reaction
Histiocytosis X
Chronic interstitial pneumonia caused by abnormal proliferation of histiocytes
90% are cigarette smokers
Symptoms: dyspnea and nonproductive cough
Can also have spontaneous pneumothorax, lytic bone lesions, and diabetes insipidus
CXR: honeycomb appearance, Ct scan shows cystic lesions
Treatment: corticosteroids and lung transplantation
Pulmonary alveolar protenosis
Accumulation of surfactant lke protein and phospholipids in alveoli
Symptoms: dry cough, dyspnea, hypoxia, and rales
CXR: ground glass appearance with bilateral alveolar infiltrates that resemble a bat shape
Diagnosis: lung biopsy required for definitive diagnosis
Treatment: lung lavage or Granulocyte-colony-stimulating factor
Do not give steroids due to increased risk of infection
Cryptogenic organizing pneumonitis
Inflammatory lung disease with similar features to pneumonia
Features: cough, dyspnea, flu-like symptoms
CXR: bilateral patchy infiltrates
Treatment: spontaneous recovery or corticosteroids
Radiation pneumonitis
Interstitial pulmonary inflammation
Acute: 1-6 months after irradiation
Chronic: 1-2 years after
Features: low-grade fever, cough, chest fullness, dyspnea, pleuritic chest pain, hemoptysis, ARDS
CXR: normal
CT scan: best study-diffuse infiltrates, ground glass density, consolidation, pleural/pericardial effusions
Treatment: corticosteroids
Complications of Ventilators
Anxiety, agitation and discomfort-use benzos for sedation
opiods for analgesia
Tracheal secretions: suction on the reg
Nosocomial pneumonia: if >3 days
Barotrauma-high airway pressures
O2 toxicity: if FiO2 greater than .6 for 2-3 days
Hypotension: increased intrathoracic pressure decreases venous return
Tracheomalacia: softening of tracheal cartilage if greater than 2 weeks
Stress ulcers and cholestasis
Gardner’s syndrome
Colon Polyps plus osteomas, dental abnormalities, benign soft tissues tumors, desmoid tumors, sebaceous cysts
Risk of Colorectal cancer is 100% by 40
Turcot’s syndrome
AR
Polyps plus cerebellar medulloblastoma or gliobalstoma multiforme
Angiodysplasia of the colon
Tortuous, dilated veins in submucosa of he colon-usually proximal wall
Common cause of lower GI bleeding
Diagnosed by colonscopy
90% bleeding stops spontaneously
Treated with: colonscopic coagulation
persists-right hemicolectomy
Ogilvies Syndrome
Signs, symptoms and radiological evidence of large bowel obstruction are present but there is no mechanical obstruction
Causes: recent surgery or trauma, serious medical illnesses and medications (narcotics, psychotropic drugs, anticholinergics)
Treatment: stop offending agent IV fluids, electrolyte repletion Decompression with enemas or nasogastric suction Colonoscopic decompression Surgical decompression is last resort
hepatorenal syndrome
indicates end stage liver disease
Progressive renal failure in advanced liver disease, secondary to renal hypoperfusion from vasoconstriction of renal vessels
Precipitated by infection or diuretics
Clinical: azotemia, oliguria, hyponatremia,, hypotension, low urine sodium (
Spontaneous bacterial periotnitis
Infected ascitic fluid-occurs in 20% of patients hospitalized for ascites
High mortality rate (associated with ESLD)
Etiologic agents: E. Coli (most common), Klebsiella, Strep. pneumo
Clinical: abdominal pain, fever, vomiting, rebound tenderness, SBP may lead to sepsis
Diagnosis: established by paracentesis
WBbs >500 PMN>250
Culture fluid
Treatment: broad sprectrum antibiotics
Repeat paracentesis in 2-3 days to decrease ascitic fluid PMN to less than 250
Hepatic Hydrothorax
Tansudative pleural effusion more common on right side
Treatment: liver transplantation
Therapeutic thorancentesis
salt restriction and diuretics
Refractory: transjugular intrhepatic portosystemic shunt
Hemobilia
Blood draining into duodenum via common bile duct
Causes: trauma, papillary thyroid carcinoma, surgery, tumors, infection
Clinical: GI bleeding, jaundice, and RUQ pain
Diagnosis: arteriogram
Upper GI endoscopy shows blood coming out of the ampulla of Vater
Treatment: resuscitation
Severe bleeding: surgery-ligation of hepatic arteries or embolization of vessel
Aortoenteric fistula
Rare but lethal cause of GI bleed
history of aortic graft surgery who has a small GI bleed involving the duodenum before massive fatal hemorhage hours to weeks later
Endoscopy or surgery during small window to prevent death