Pulmonary and Cardio Treatments Flashcards
PE treatment
Provoked DVT of calf or upper extremity: 3 months of anticoagulation
Provoked DVT of proximal leg: 6 months of anticoagulation
Unprovoked, malgnancy or antiphospholipid: indefinite
IVC filter: prevents recurrent PE, during active bleeding or other contraindication
Primary: clot dissolution with thrombolysis or surgical removal reserved for those with high risk of adverse outcomes: RHF or hypotension
Secondary: Anticoagulation-unfractionated heparin (must be monitered every 4-6 hrs) right away
subcutaneous LMWH (enoxaprin or tinzaparin) or direct factor Xa inhibitor (fondaparinux)
Warfarin-overlapped with UFH or LMWH for 5 days-INR goal of 2.5 for 2 consecutive days
Duration of treatment relates to risk of recurrence
PE imaging choice
chest CT with intravenous contrast
CT contraindicated (renal insufficiency or contrast allergy)-use V/Q scan
Both negative but still have a suspicion=lower extremity ultrasound
Hemodynamically unstable patient in A. Fib
Meaning shock or hypotension symptoms
Urgent direct cardioversion
Electrical better than pharmocological
Pharm if electrical failed: procainamide, flecainide, sotalol or amiordarone
Hemodynamically stable patient in A. fib
Ventricular rate control-IV Beta blockers, CCBs or digoxin
Persistently symptomatic A. fib
electrical cardioversion with 3 to 4 weeks of anticoagulation prior to and after cardioversion
Goal INR or 2-3
Wolf Parkinson Wright Diagnosis and treatment
Diagnosis: narrow complex tachycardia, short PR interval, delta wave
Treatment: procainamide, quinidine or amiordarone
Radiofrequency catheter ablation
drugs to avoid in wolf parkinson wright syndrome
Beta blockers
Verapamil
Other AV nodal blockers
May paradoxically increase the ventricular rate
Best initial test for all forms of chest pain
ECG
Treatment of Angina
Mild (normal EF,, mild angina, single vessel disease)
Nitrates and B blockers
Moderate (normal EF, moderate angina, two vessel disease)
Try nitrates and B blockers
consider coronary angiography to assess suitability for revascularization-PCI or CABG
Severe (decreased EF, severe angina, and three vessel/LAD)
Coronary angiography and consider CABG-decrease symptoms
Treatment of unstable angina
Acute Aspirin +Clopidogrel-9-12 mos BB blockers Enoxaparin (LMWH)-2 days Nitrates Oxygen Abciximab, tirofiban
After acute
Continue aspirin, B blockers, and nitrates
Reduce smoking, weight, diabetes, HTN, hyperlipidemia
Treatment of cardiac tamponade
relief of pericardial pressure either echocardiographically guided pericardiocentesis or surgical pericardial window
While waiting treat with IV fluids (cardiac tamponade is preload dependent)
Treatment of constrictive pericariditis
Resection of pericardium
Treatment of acute MI
Aspirin/heparin Beta blockers Nitrates morphine supplemental O2
ST segment elevation-thrombolytics within 1-3 hours
PCI perferred within 90 mins
when to use angioplasty in acute MI
less than 1 hour Contraindication to lytic therapy-major recent surgery active internal bleeding, or suspected acortic dissection, severe hypertension, or a prior history of hemorrhagic stroke Cardiogenic shock Refractory ventricular arrythmia large infract size
Treatment of COPD
Most importantly smoking cessation
B2 agonists for symptomatic relief
Anticholinergic (ipratropium bromide)-longer acting
Both together work better than separate
Inhaled corticosteroids (budesonide, fluticasone)-significant symptoms or repeated exacerbations
Systemic Corticosteroids and antibiotics (azithromycin/levofloxacin) for acute exacerbations, change in sputum, or increased SOB (IV methylpredinsolone)
Possible noninvasive positive pressure ventilation may be necessary
Theophylline if unresponsive to everything else
O2-imporves survival and QOL of those with COPD and chronic hypoxemia (pO2 55%)
Flu vaccine annually
Strep pnemo vaccine every 5-6 yrs if >65 or have severe disease
intubation Acute respiratory acidosis and CO2 retention
Treatment of asthma
Inhaled B2 agonists for acute attacks Long acting (salmeterol)-nighttime and exercise induced
Inhaled corticosteroids for moderate to severe asthma
Montelukast-prophylaxis of mild exercise induced and moderate persistent asthma
Cromolyn sodium/nedocromil sodium-prophylaxis
Treatment of acute exacerbation of asthma requiring hospital admission
Inhaled B2 agonist with ipratropium-first line
Corticosteroids-IV or orally
IV Mg- if not responsive to other therapies
Antiobiotics
Endotracheal intubation if in respiratory failure-hypercapnia
Treatment of Bronchiectasis
antiobiotics for acute exacerbations
Hydration
Chest physiotherapy-postural drainage, chest percussion
Inhaled bronchodilators
Treatment of CF
pancreatic enzyme replacement Fat soluble vitamin supplements Chest physical therapy Vaccinations-influenza and pneumococcal Antibiotics Inhaled recombinant human deoxyribonuclease
Treatment of pleural effusions
Transudative (CHF, cirrhosis, nephrotic syndrome)
Diuretics and sodium restriction
Therapeutic thorancentesis if causing dyspnea
Exudative: treat underlying disease
Thorancentesis
Pleural effusion with pneumonia
Antibiotics
Complicated or empyema: chest tube drainage, intrapleural injection of thromboytic agents, surgical lysis of adhesions
Treatment of empyema
aggressive drainage of the pleura sometimes repetitive
If severe and persistent rib resection and open drainage
Treatment of pneumothorax
Primary spontaneous
small and asymptomatic: observation or one way valve chest tube
Large or patient is symptomatic: supplemental O2
Chest tube
Secondary complicated pneumothoraxx
chest tube drainage
Treatment of tension pneumothorax
medical emergency-do not obtain CXR
Chest decompression with large bore needle (2nd or 3rd intercostal space in MCL)
Followed by chest tube placement
Sarcoidosis treatment
Systemic corticosteroids
Methotrexate for those refractory to corticosteroids
Wegener’s granulomatosis treatment
immunosuppressive agents and glucocorticoids
churg-strauss syndrome treatment
glucocorticoids
Treatment of berylliosis
glucocorticoid therapy
Treatment of Goodpastures syndrome
Plasmapharesis, cyclophosphamide, and corticosteroids
Treatment of idiopathic pulmonary fibrosis
Most do not respond to anything
Supplemental O2
Corticosteroids with or without cyclophosphamide
lung transplantation
Hypercarbic respiratory failure treatment
High flow venturi mask preferred because one can control oxygenation more precisely
NPPV given to patients in impending respiratory failure in an attempt to avoid intubation and mechanical ventilation -patient should be neurologically intact, awake and cooperative