Random Cardio 2 Flashcards
Homeometric regulation
varies contractile force by changes in maximum velocity of shortening
NOT dependent on a change in rest length
Starling curve
Heterometric
Why might inc HR impair coronary BF?
Tachycardia shortens the diastolic interval, which may impair coronary flow since these vessels are perfused during diastole.
What change to BP may impair coronary BF?
any influence that lowers aortic diastolic pressure may compromise coronary blood flow
large fraction of total coronary flow occurs during diastole, so driving pressure at the entrance of the coronary arteries during diastole is an important factor to assure adequate flow
baroreceptor stim
respond to stretch (increased BP)
dec sympathetic firing
dec BP
inc parasympathetic stim
venous changes
inc venous capacitance
dec venous return
isoproterenol
non-specific B-agonist used in tx of bradycardia
“post-conversion pause”
Atrial fibrillation and sinus node dysfunction often coexist
rheumatic endocarditis lesions
Adherent, sterile, located at the closure margins and small and regular.
____ are the two most common causes of acquired valvular disease.
Calcific aortic stenosis and mitral valve prolapse
hypercoaguable state
adenoCA
–>
Non-bacterial thrombotic endocarditis
An anterolateral infarct indicates occlusion of which vessel?
LAD
The more severe the aortic stenosis, the ___ the murmur peaks.
later
large V wave
mitral regurg
endothelin
powerful vasoconstrictor
CK-MB returns to baseline
3-4 d
troponin returns to baseline
10 d
contraindicated in NSTEMI tx
lytic therapy (alteplase (tPA), reteplase (rPA) and tenekteplase (TNK-tPA))
transfer to Cath lab
IV heparin
aspirin
aspirin is approved for use in prevent CVD in which pt
aspirin is used for the secondary prevention of CAD and when the 10 year risk of ASCVD exceeds 10%
b-blocker to avoid in angina
acebutolol (intrinsic sympathetic activity)
type a dissection
proximal, more common
tx: surgical