Random Cardio 2 Flashcards

1
Q

Homeometric regulation

A

varies contractile force by changes in maximum velocity of shortening

NOT dependent on a change in rest length

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2
Q

Starling curve

A

Heterometric

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3
Q

Why might inc HR impair coronary BF?

A

Tachycardia shortens the diastolic interval, which may impair coronary flow since these vessels are perfused during diastole.

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4
Q

What change to BP may impair coronary BF?

A

any influence that lowers aortic diastolic pressure may compromise coronary blood flow

large fraction of total coronary flow occurs during diastole, so driving pressure at the entrance of the coronary arteries during diastole is an important factor to assure adequate flow

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5
Q

baroreceptor stim

A

respond to stretch (increased BP)

dec sympathetic firing

dec BP

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6
Q

inc parasympathetic stim

venous changes

A

inc venous capacitance

dec venous return

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7
Q

isoproterenol

A

non-specific B-agonist used in tx of bradycardia

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8
Q

“post-conversion pause”

A

Atrial fibrillation and sinus node dysfunction often coexist

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9
Q

rheumatic endocarditis lesions

A

Adherent, sterile, located at the closure margins and small and regular.

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10
Q

____ are the two most common causes of acquired valvular disease.

A

Calcific aortic stenosis and mitral valve prolapse

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11
Q

hypercoaguable state
adenoCA

–>

A

Non-bacterial thrombotic endocarditis

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12
Q

An anterolateral infarct indicates occlusion of which vessel?

A

LAD

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13
Q

The more severe the aortic stenosis, the ___ the murmur peaks.

A

later

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14
Q

large V wave

A

mitral regurg

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15
Q

endothelin

A

powerful vasoconstrictor

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16
Q

CK-MB returns to baseline

A

3-4 d

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17
Q

troponin returns to baseline

A

10 d

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18
Q

contraindicated in NSTEMI tx

A

lytic therapy (alteplase (tPA), reteplase (rPA) and tenekteplase (TNK-tPA))

transfer to Cath lab
IV heparin
aspirin

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19
Q

aspirin is approved for use in prevent CVD in which pt

A

aspirin is used for the secondary prevention of CAD and when the 10 year risk of ASCVD exceeds 10%

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20
Q

b-blocker to avoid in angina

A

acebutolol (intrinsic sympathetic activity)

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21
Q

type a dissection

A

proximal, more common

tx: surgical

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22
Q

type b dissection

A

descending, but can propagate up

tx: control HTN/sx. surgery has HIGH MORTALITY

23
Q

most comm EKG abnormality in acute chagas

24
Q

hematoxyphil bodies

A

Libman sacks (SLE)

25
The aldosterone antagonists spironolactone and eplerenone have been shown to significantly reduce the mortality of patients with
heart failure and reduced LVEF
26
BNP
``` vasodilator promotes diuresis (favorable in HF) ```
27
Kussmal's
Konstrictive Pericarditis inc JVP w/ inspiration, ventricle cannot accept inc VR
28
brisk y descent
Constrictive pericarditis rapid relaxation and suction of right atrium
29
LE edema tamponade or constrictive pericarditis?
Constrictive pericarditis
30
rapid x descent
tamponade
31
blunted y descent
tamponade
32
CHADS score
risk fx for stroke in afib pt ``` CHF HTN Age >75 diabetes S2, stroke ```
33
L axis deviation
-30 - -90
34
R axis deviation
+90 - +180
35
lidocaine does not have a significant effect on
AV nodal conduction
36
P waves inverted in II, III, aVF
ectopic atrial arrhythmia
37
Trifascicular block
first degree AV block, RBBB and LAFB
38
foam cell
macrophage, smc
39
fixed split S2
ASD | inc BF on R side of heart
40
L --> R shunt L vs R sided COP?
Left cardiac output < right cardiac output
41
small quiet heart
constrictive pericarditis
42
Which malignancies are particularly likely to metastasize to heart?
malignant melanomas
43
tumors comm assoc w/ cardiac involvement
``` malignant melanoma lung breast soft tissue sarcoma renal esophageal hepatocellular thyroid ```
44
shock w/ highest pulm a. O2 saturation
septic shock non-specific arterial vasodilation and elevated cardiac output such that less oxygen is extracted by peripheral tissues than normal leading to a higher oxygen saturation
45
Matrix metalloproteinases degrade ____ support that prevents a plaque from rupturing.
collagen
46
A statin (HMG-CoA Reductase Inhibitor) is recommended when the 10-year ASCVD risk is greater than
7.5%
47
congenital rubella
PA stenosis | PDA
48
Beck's triad
elevated JVP hypOtension muffled heart sounds
49
most comm cause of new systolic HFrEF
ischemic heart disease
50
increase in oxygen saturation between the mixed venous sample (from the vena cava or right atrium) and the pulmonary artery is caused by
VSD
51
HR < __ indicates bradycardia
60
52
ST segment depression in V4-V6 with a biphasic T-wave
LVH
53
diffuse left ventricular impulse
DCM
54
monomorphic VT
old scar caused by an MI prod a reentrant arrhythmia