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Question 0

Mannitol

Answer 0

Osmotic diuretic

Used in acute raised ICP

Question 1

Duloxetine

Answer 1

Na and serotonin reuptake inhibitor

For depression and incontinence

Question 2

Calcium gluconate

Answer 2

Cardio protective agent in hypokalaemia (prevents arrhythmia)
Overdose causes arrhythmia

Question 3

Bisphosphanates

Answer 3

Given in osteoporosis

Promote bone formation

Question 4

Disulfiram

Answer 4

Inhibitor of aldehyde dehydrogenase
Used in alcoholism
Causes symptoms of hangover but more quickly

Question 5

Phenoxybenzamine

Answer 5

Alpha 1 adrenoceptor blocker used in hypertension in pheochromocytoma

Question 6

Carbimazole

Answer 6

Treatment for hyperthyroid

Prevents incorporation of iodine to thyroglobulin

Question 7

Drugs with zero order kinetics in overdose

Answer 7

Aspirin
Phenytoin
Verapamil
Fluoxetine

Question 8

Drugs affecting absorption of other drugs

Answer 8

Opiates and atropine slow gut motility, so increase
Metaclopramide speeds up the gut, so decreases
Calcium salts bind to tetracyclines, preventing their uptake
Cholestyramine binding prevents digoxin and warfarin uptake

Question 9

Valerian

Answer 9

Herbal remedy for insomnia and sleep disorders.

Careful when prescribing sedatives, but no ADRs proven.

Question 10

Oxybutynin

Answer 10

Anti muscarinic

Used in overactive bladder syndrome

Question 11

Allopurinol

Answer 11

Xanthine oxidase inhibitor good in CKD

Used to prevent gout as lowers urate