Anaesthetics Flashcards
Examples of IV anaesthetics
Propofol, barbiturates, etomidate, ketamine
Examples of anaesthetic gases
N2O, diethyl ether, chloroform, cyclopropane, halothane, fluroxane, isofluorane
What is MAC?
Measure of potency for volatile agents.
What does N2O do to MAC?
Generally increases so doses can be reduced.
How is GABA used in anaesthesia?
Most anaesthetic agents potentiate its effects to depress CNS activity
Via chlorine conductance.
What parts of the brain does anaesthesia target?
Reticular formation (depressed) Hippocampus (depressed) Brain stem (depressed) Spine - dorsal horn and motor neuronal activity depressed.
Local anaesthetics characteristics
Lipid solubility (potency) Dissociation constant (onset) Chemical link (metabolism) Protein binding (T1/2)
Bupivacaine
Local anaesthetic
Lidocaine
Local anaesthetic
Ropivacaine
Local anaesthetic
Procaine
Local anaesthetic
Propofol
IV anaesthetic
Barbituates
IV anaesthetic
Etomidate
IV anaesthetic
Ketamine
IV anaesthetic