Corticosteroids Flashcards
0
Q
Glucocorticoid ADRs
A
Cushings Sodium and water retention Adrenal insufficiency Infection Psychiatric profile
1
Q
Glucocorticoid actions
A
Increased blood glucose Increased proteolysis Redistribution of lipids Inhibition of osteoblast function Inhibit B and T cell responses, reduce transcription of cytokines, reduce cell adhesion by leukocytes and reduce phagocytosis.
2
Q
Glucocorticoid metabolism
A
Uses cyp450 so affected by inducers and inhibitors
3
Q
Glucocorticoid uses
A
Inflammatory diseases Immunosuppression Malignancy Adrenal insufficiency Diagnosis of cushing's
