Radiation Chemistry Flashcards
What is the critical target?
DNA
Period following irradiation and prior to changes occurring in the cell
Latent period
What are stochastic radiation effects?
Random, no threshold dose exists. The effect is “all or nothing” (increasing the dose will increase the possibility of an effect occurring but not it’s intensity)
What are nonstochastic radiation effects?
Known, meaning threshold doses have been determined. Immediate to time-delayed effects such as cataracts, cancer and the three syndromes: Hemopoietic, Gastrointestinal, and CNS
Biologic changes only occur after a _______ _______
Latent Period
What is direct interaction?
DNA is affected directly by the radiation
What is indirect interaction?
Radiation effects the medium in which the organelles are suspected which in turn effects the cells ability to reproduce
The transfer of the incorrect genetic code to one of the daughter cells
Critical Consequence
Ionization of the water in the body causes an effect on the _______ ________
Critical Target
Differences between direct and indirect radiation effects?
Direct effect directly damages the DNA. Indirect has greater probability of occurrence and is damage that occurs through chemical interactions and free radical formation (especially of hydrogen peroxide and hydroperoxyl)