RAAS Flashcards

1
Q

Where is aldosterone produced?

A

the adrenal cortex

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2
Q

what type of hormone is aldosterone?

A

steroid

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3
Q

What is the function of aldosterone ?

A

Stimulates Na+ reabsorption in the distal tubules and collecting ducts

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4
Q

What stimulates aldosterone release?

A

angiotensin II

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5
Q

What does angiotensin II stimulate the release of from the adrenal cortex?

A

aldosterone

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6
Q

How is angiotensin II formed from angiotensin I?

A

angiotensin-converting enzyme

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7
Q

What is the function of angiotensin-converting enzyme ?

A

converts angiotensin I to angiotensin II

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8
Q

What splits angiotensin I from angiotensiogen?

A

renin

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9
Q

Why is aldosterone slower acting than vasopressin?

A

aldosterone is a steriod and vasopressin is a peptide

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10
Q

Describe aldosterone levels in a person who eats a high sodium diet?

A

low aldosterone levels

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11
Q

Which cells secrete renin?

A

juxtaglomerular cells

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12
Q

Where is angiotensin I converted into angiotensin II?

A

the lungs

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13
Q

How many litres of water are in a 70Kg male?

A

42L

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14
Q

What percentage of body weight is total body water?

A

60%

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15
Q

What percentage of total body weight is intracellular fluid?

A

40%

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16
Q

What percentage of total body weight is extracellular fluid ?

A

20%

17
Q

What would the osmolality of pure water be?

A

0

18
Q

What is osmolality ?

A

total number of particles in solution

19
Q

What does isotonic mean?

A

the same osmolality

20
Q

What is osmolarity?

A

the number of particles in 1 L of fluid

21
Q

What is the main contributor to extracellular fluid osmolality?

A

sodium

22
Q

What is the average urine volume per day?

A

1.5L

23
Q

What is hypernatraemia?

A

high sodium

24
Q

What is the major cation of the extracellular fluid?

A

sodium

25
Q

What is the major cation of the intracellular fluid?

A

potassium

26
Q

Which out of the ICF and ECF has more sodium?

A

ECF

27
Q

Which organ produces angiotensinogen?

A

the liver

28
Q

How does angiotensin II affect ADH secretion?

A

increases ADH secretion

29
Q

What effect does angiotensin II have in blood vessels?

A

vasoconstriction