Quiz Chapter 2 Flashcards
When a patient asks the nurse why a lower dose of intravenous pain medication is being given in the previous oral dose, what knowledge for the nearest draw on to respond to the patient?
A) medications given by IV I’m not affected by the first-pass effect
B) medications given orally bypass the portal circulatory system
C) a large percentage of an IV administered drug is metabolized into an active metabolites in the liver
D) drugs administered by IV enter the portal system prior to systemic distribution
A
What is an alternate name for biotransformation of a drug?
Metabolism
Which action, when performed by the nurse, will increase the absorption of a medication administered intramuscularly?
A) applying cold pack to the injection site B) lowering the extremity below the level of the heart C) administering the medication via the Z-track method D) massaging the site after injection
D
What is the study of the physiochemical properties of drugs and how the influence the body called? A) pharmacokinetics B) pharmacotherapeutics C) pharmacodynamics D) pharmacology
C
Drug half-life is defined as the amount of time required for 50% of a drug to:
A) be absorbed by the body be) exert a response C) be eliminated by the body D) reach a therapeutic level
C
Patients with renal failure would most likely have problems with drug:
A) excretion B) absorption C) metabolism D) distribution
A
The nurse needs to be aware that which factors will affect the absorption of orally administered medications? (Select all that apply):
A) presence of food in the stomach B) pH of the stomach C) patient position upon intake of medication D) form of drug preparation E) time of day
A, B, D, E,
The nurse understands that drugs exert their actions on the body by (select all that apply):
A) interacting with receptors B) making the cell perform a new function C) inhibiting the action of a specific enzyme D) altering metabolic chemical processes
A, C, D
Highly protein-bound drugs:
A) increase the risk of drug-drug interactions
B) typically provide a short duration of action
C) must be administered with 8 ounces of water
D) have a decreased effect in patients with a low albumin level
A
To achieve the most rapid onset of action, the healthcare provider will prescribe the medication to be administered by which route? A) subcutaneously B) intravenously C) intramuscularly D) intrathecally
B
Pharmacokinetics involves the study of: A) physiologic interactions of drugs B) distribution rates among various body compartments C) interactions between various drugs D) adverse reactions to medications
B
What is the ratio between the drugs therapeutic effects and toxic effects called? A) tolerance B) cumulative effect C) therapeutic index D) affinity
C
A drug given by which route is altered by the first-past effect?
A) sub lingual B) subcutaneous C) oral D) intravenous
C) oral
If two drugs have the same bioavailability and same concentration active ingredient, there is said to be – –, example: a brand-name drug in the same generic drug
Bioequivalent Drugs
P. 22
When a drug is bound to albumin:
A) drug is readily available for absorption
B) patient is @ increased risk for drug toxicity
C) too large to pass through the walls of blood capillaries & tissues
D) route of admin. was oral
C)
