Quiz-Ch. 15 Anti-Parkinson's Drugs Flashcards

0
Q

Which antiparkinson drug causes an increase in the levels of dopamine energetic stimulation in the central nervous system and therefore allows a decrease dose of other medications?

A) levodopa
B) Carbidopa
C) Selegiline
D) diphenhydramine

A

C) Selegiline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

The patient with Parkinson’s disease who has been positively responding to carbidopa-levodopa (Sinemet) suddenly develops a relapse of symptoms. Which explanation by the nurse is appropriate?

Hey) “you have obviously develop resistance to your current medication and will have to be switched to another job.”

B) “this is an atypical response. Unfortunately, there are no other options of jugs therapy to give you.”

C) “this is called the “on-off phenomenal”. Your healthcare provider can change her medication regimen slightly to help diminish this effect.”

D) “you just need to keep taking your medication in these effects will go away.”

A

C) “this is the on-off phenomenon. Your healthcare provider can change her medication regimen slightly to help diminish this effect”.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The patient asks the nurse to explain the difference between carbidopa-levodopa (Sinemet) and ropinirole (Requip). How will the nurse respond?

A) ropinirole is a dopamine agonist that has fewer side effects than carbidopa-levodopa

B) carbidopa-levodopa is less effective than ropinirole in treating the symptoms of Parkinson’s disease

C) both drugs have the same pharmacodynamic and side effect profiles

D) carbidopa-levodopa ask as a dopamine agonist, whereas ropinirole directly replaces dopamine

A

A) ropinirole is a dopamine agonist that has fewer side effects than carbidopa-levodopa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the goal of pharmacologic therapy and treating Parkinson’s disease?

A) to increase the amount of acetylcholine at the presynaptic neurons

B) to decrease the amount of dopamine available in the substantia nigra

C) to balance cholinergic and dopaminergic activity in the brain

D) to block dopamine receptors in both presynaptic and postsynaptic neurons

A

C) to balance cholinergic and dopaminergic activity in the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

The nurse is caring for a patient with Parkinson’s disease. The patient has been taking entacapone (Comtan) for the past week to treat an on-off phenomenon. The patient expresses concern over Brown-orange urine. What information will the nurse provide?

A) the patient may be developing renal failure

B) The patient may be developing a product failure

C) Brown-orange urine signifies a lack of fluid intake

D) this is a normal occurrence related to entacapone (Comtan).

A

D) this is a normal occurrence related to entacapone (Comtan).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

A patient with Parkinson’s disease is discussing a recent bout of insomnia with the nurse. The patient asks if he can take an old prescription he has to treat insomnia. What does the nurse know about the use of benzodiazepines in patients taking levodopa?

A) use of benzodiazepines decrease the therapeutic effect of the levodopa and they result in an increase in symptoms of Parkinson’s disease
Because parentheses use of duck benzodiazepines increases the therapeutic effect of the levodopa and then result in a decrease in the symptoms of Parkinson’s disease
C) use of benzodiazepines decreases the therapeutic effect of the levodopa and Mary’s old and a decrease in symptoms of Parkinson’s disease

D) use of benzodiazepines increased therapeutic effect of the levodopa and I result in an increase in symptoms of Parkinson’s disease

A

A) Use of benzodiazepines decrease the therapeutic effect of the levadopa and may result in an increase in the symptoms of Parkinson’s disease.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The patient who has been taking anti-Parkinson’s medication for years begins to have increased symptoms on a constant basis. And documenting the symptoms, what term will the nurse use?

A) on-off phenomenon
B) wearing-off phenomenon
C) chorea
D) dystonia

A

B) wearing-off phenomenon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

When teaching a patient about carbidopa-levodopa (Sinemet), what information will the nurse include in the teaching?

A) carbidopa decreases levodopa’s conversion in the periphery, increasing the levodopa available to cross the blood-brain barrier

B) carbidopa increases levodopa’s conversion in the periphery, enhancing the amount of dopamine available to the brain

C) getting both drugs together minimize the side effects

D) carbidopa crosses the blood brain barrier and to increase the metabolism of levodopa to dopamine in the brain

A

A) carbidopa decreases levodopa’s conversion in the periphery, increasing the levodopa available to cross the blood-brain barrier

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

The nurse is providing care for a patient who is been diagnosed with Parkinson’s disease. The patient is also an early stage liver failure. What class of medications, if prescribed, would the nurse question?

A) dopamine modulator
B) Anticholinergics
C) COMT inhibitors
D) Ergot derivative

A

C) COMT inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly