Chapter 40- Antiviral Drugs

Question 0

What is the process of viral Fusion?

Answer 0

Virions attach themselves to host cells in preparation for infecting the cells.

Question 1

Acquired Immunodeficiency Syndrome (AIDS):

Answer 1

Infection caused by the human immunodeficiency virus (HIV), which weakens the host’s I.S., giving rise to opportunistic infections
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Question 2

Layers of a virus particles:

Answer 2

1. Envelope

2.

Question 3

4 routes of viral entry:

Answer 3

1. Inhalation through resp. tract
2. Ingestion via GI tract
3. Transplacentally
4. Inoculation: sexual contact, blood transfusions, needles, organ transplantation, & bites

Question 4

What is the cytopathic effect?

Answer 4

The changes in the cell associated with viral replication

Question 5

What is viral teansformation?

Answer 5

Mutation of the host cell DNA or RNA and can result in malignant (cancerous) host cells.
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Question 6

What are oncogenic viruses?

Answer 6

Viruses that can induce cancer in a host cell by changing the cell DNA or RNA.
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Question 7

Explain non-specific immune response to viral infection:

Answer 7

Phagocytosis of viral particles by leukocytes; release of cytokines from leukocytes; cell-mediated: does not involve anti-bodies that are specific for a given antigen;
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Question 8

Explain specific immune response to viruses:

Answer 8

Includes the production of anti-bodies from B lymphocytes (B cells), immunoglobulins. Also called humoral immunity.

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