Quiz 5 Flashcards
what is the main function of the circulatory system
delivering oxygen and nutrients to tissues
what are the two divisions of the circulatory system?
the blood vascular (cardiovascular) system and the lymphatic vascular system
lymph nodes
surve filtration and immune surveillance before returning to the blood circulation
what does the tunica intima include?
epithelium and CT
what does the tunica media include?
muscle and supporting CT
what does the tunica adventitia include?
advential CT
what does the tunica intima corrsond to in the heart?
endocardium
what does the tunica media correspond to in the heart?
the myocardium
what does the tunica adventitia correspond to in the heart
the subepicardium
what are the high pressure conducting vessels?
the elastic and muscular arteries
what are the blood pressure control vessels?
arteriole
what are the leukocyte escape vessels
postcapillary venules
what are the low pressure capacitance vessels
veins and venules
most of the blood in the body is where?
in veins
mediastinum
the central region of the thoracic cavity located between the left and right pleural sacs.
what are the vessels entering the heart?
superior vena cava and inferior vena cava
what are the vessels leaving the heart?
the pulmonary trunk and aorta
describe the rhythmic contractions of the heart
Both atria contract simultaneously during atrial systole and relax simultaneously during atrial diastole. Both ventricles contract simultaneously during ventricular systole and relax simultaneously during ventricular diastole.
describe the pumonary circut
1)the right atrium receives deoxygenated blood through the superior vena cava, inferior vena cava, and coronary sinus.
2)The right atrium pumps blood through the right atrioventricular (tricuspid) valve to the right ventricle.
3)The right ventricle pumps blood through the pulmonary valve to the pulmonary trunk and left and right pulmonary arteries.
4)The pulmonary arteries and branches deliver deoxygenated blood to the lung capillary beds for oxygenation.
describe the systemic circuit
1)the left atrium receives oxygenated blood from the lung capillary beds through the pulmonary veins.
2)The left atrium pumps blood through the left atrioventricular (mitral) valve to the left ventricle.
3)The left ventricle pumps blood through the aortic valve to the aorta.
4)The aorta and branches deliver oxygenated blood to capillary beds throughout the body.
describe the hepatic portal circuit
1) the liver receives oxygenated blood through the hepatic arteries and oxygen-depleted but nutrient-rich blood from the gastrointestinal tract and spleen through the hepatic portal vein.
2) Blood from both vessels percolates through a specialized capillary bed in the liver, the hepatic sinusoids, before leaving the liver to enter the inferior vena cava
what is a thrombus
a clot that forms within the cardiovascular system during life
what is an embolus?
a thrombus, detached atheromatous plaque, or other foreign body that travels within the cardiovascular system and lodges in a vessel, fully or partially occluding the vessel.
what direction does an arterial embolus travel?
An arterial embolus travels away from the heart through progressively smaller vessels
what direction does a venous embolus travel?
travels toward the heart through progressively larger vessels
what is a fibrous pericardium?
A dense connective tissue sleeve that surrounds the heart
what is the serous pericardium?
-A closed mesothelial sac
-lines the inner surface of the fibrous pericardium
where do the left and right coronary arteries supply?
the first branches of the aorta, supply the heart itself
Fibrillation
spontaneous and irregular contraction of cardiac myocytes
what initiates ventricualr contraction
purkinje fibers
what is the difference with ventricular ad atrial fibrilation?
ventricular fibrilation is not compatabile with life atrial fibrilation can survive
Cardiac ‘skeleton’
a pretzel-like configuration of dense connective tissue between the atria and ventricles of the heart
annuli
ring of the cardiac skeleton surround and stabilize the valve cusps and provide attachment for both atrial and ventricular cardiac muscle
the area in the heart that has alot of adipose tissue is
epicardium and subepicardium
the area enclosing the heart by the purkinje fibers is
the endocardium and subendcarium
what are the structures at the bottom
purkinje fibers
what are lamellar units
in elastic arteries alternating layers of elastin and smooth muscle
what is the thickest layer in elastic arteries
the tunica media
what is the nervi vasorum
sympathertic motor fiber in the smooth muscle
what is the bottom arrow pointing to>
vasa vasorum
what is this pointing to?
lamellar unit
what is this staining and why is it wavy
elasin
wavy bc waiting to be stretched
what is turbulance most often caused by?
sharp time,branch point, or
closing
what is a aneurysm?
balloning of the blood vessel becuase of weakness of the vessel wall
what is a dissection?
intimal tear and blood leaks into the tunica
aortic dissection
blood in the tunica intima of the aortia creating a false lumen
what are most arteries?
muscular arteries
what is the main purpose of muscular arteries?
control resistance
how any layers of smooth muscle do arterioles have?
1-2 cell lyers
what is the size of a capillary?
1 RBC thick
what is the size of a venule
3 RBC thick
what are capillaries missing
no media or adventita, or smooth muscle
what surrounds capillaries?
pericytes
where are continuous capillaries found?
Muscle tissue, connective tissue, lung, skin, the central nervous system, and the placent
connected with tight juctions
where are fenestrated capillaries?
Intestinal mucosa, gallbladder, endocrine and exocrine glands (pancreas), and kidney
what are fenestrated capillaries
Endothelial cells have numerous fenestrations or pores, usually closed by diaphragms that restrict passage of large molecules such as proteins
Although the endothelial cells are fenestrated, the basal lamina is continuous
where are sinusoidal capillaries?
Liver, spleen, bone marrow, adenohypophysis, and suprarenal medulla
what are sinusoidal capillaries?
Endothelial cells with large fenestrations which are also separated by large intercellular junctions. Basal lamina discontinuous or absent (liver).
what veins have valves
only limb veins
what is the thickest layer in veins?
the adventitia
what are special veins
-Large veins closer to heart
-have circular smooth muscle 2-15 layers and collagen fibers
-also have longitudial smooth muscle in subendothelial CT
superior and inferior vena cava,
brachiocephalic veins, portal vein, subclavian veins
what is the fuction of lymphatic capillaries?
Absorption of tissue fluid, waste products, and cell debris.
what areas dont have lymphatic capillaries?
cartilage, bone, bone marrow, thymus, placenta, cornea, and teeth
decribe the lympatic drainage
uneven
what is edema
accumulation of excess fluid in tissue spaces
what leads to edema?
An increase in capillary hydrostatic pressure or a decrease in plasma osmotic pressure may lead to edema
Microfilariae
Microfilariae are the embryonic forms of adult nematodes living in the blood of infected individuals. Microfiliariae may block lymphatic vessels, causing massive lymphedema.
what vasculature does atherosclerosis primarily affect?
elastic and muscular arteries
describe the formation of atherosclerosis
1)endothelial injury causes INCREASED PERMEABILITY and INCREASED PLATELET AND MONOCYTE ADHESION. Low density lipid (LDL) and monocytes enter the subendothelial connective tissue.
2)Monocytes are activated as MACROPHAGES which engulf lipids and oxidized lipids. Factor release from endothelial cells, platelets, and macrophages induces SMOOTH MUSCLE CELL RECRUITMENT from tunica media and/or circulating SMC precursors.
3) Ongoing EXTRACELLULAR AND INTRACELLULAR LIPID ACCUMULATION. Intracellular lipid in both smooth muscle cells and macrophages (now foam cells). Fatty streaks are now apparent on the artery lumen.
4) atherosclerotic plaque form
what is this showing
Coronary artery atherosclerosis
what is a flap
a flap is a piece of tissue transferred with the blood supply
what is a graft?
a graft is a peice of tissue transferred without the blood supply
what are the prominate vasoconstrictors?
endothelin, thromboxane, angiotension II and ADH (vasopressin)
what are the prominate vasodilators
nitric oxide, ANP, adenosine, prostacyclin, and B-receptor agonist
how does sympathetic activation change blood flow?
it shunts blood away from lymphatics and towards musclle tissue
what is a baroreceptor?
a baroreceptor is a specialized sensory innervation of the larger arteries that senses information about stretching of the rescular wall+ sends it to the brain stem
what is orthostatic hypotension
loss of the baroreflex
what is vasculogenesis
the process by which vessels are formed
what is angiogenesis
the process by which vessels elaborate from exsisting vessels
label
label
label
what are both of the lines pointing to
top capillary
bottom arteriole
label
what is a valve
an extension of the ensothelial lining ensuring one way flow
what are some charateristics to help you recognize lymphatic vessels
The cells are not held in place as well as those of the veins, and their nuclei usually protrude into the vessel lumen. The smaller vessels have an angular appearance to their walls that is not apparent in veins, and the larger vessels may have valves within them
what is this pointing to?
internla elastic lamina
where are vasa vasorum?
in the tunica adventitia and usually travel alongside a companion vessel
what are the layers
what do the red and blue arrows point to?
blue: cardiac vein
red: coronary artery
Ischemia
blood flow is restricted
myocardial infarction
a blockage o f blood blood flow to the heart muscle
what is the line pointing to
athrosclerosis
what is part of the upper respiratory tract?
nasal cavity, pharyx, and larynx
what is part of the lower respiratory tract
trachea, bronchi, and lungs
label this of the outer lung
what does the conducting portion of the lung do?
conducts and condisions air