last little bit after quiz 6 Flashcards

1
Q

basal cell carcinomas

A

from keratinocytes of the stratum basale, special because of their stem-cell population

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2
Q

melanomas

A

from melanocytes

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3
Q

For a carcinoma to become malignant what must happen

A

cells involved must leave their layer of origin, and migrate into unfamiliar tissue

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4
Q

radial growth stage

A

proliferating cells are confined to the epidermis

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5
Q

vertical growth stage

A

proliferating cells have invaded the dermis (crossing tissue layers)

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6
Q

during what stage, radial or vertical growth, ado cancer cells recruit a blood supply

A

during the vertical growth stage, cancerous cells recruit a blood supply for themselves (angiogenesis) and become capable of spreading to distant sites (metastasis)

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7
Q

why do the cells have those white spaces between

A

cancer cells lack desmosomes and are motile
no cellular adhastion molecules between them

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8
Q

what is the line pointing to and what is it?

A

epithelial nest: cystic structures present In CT that
represent the immune system’s attempt to”wall off “migratory cancer

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9
Q

what cells are these and why are they brown

A

-macrophages In melanoma
-In melanoma the
Macrophages are brown because they have ingesting the melaocyes

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10
Q

what is the primary branch of the mammary glands

A

lactiferous duct

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11
Q

lactiferous duct

A

leads from the surface epithelium of the nipple to one lobe of the breast

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12
Q

what is the secondary branch of mammary glands

A

interlobular ducts

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13
Q

interlobular ducts

A

a duct that leads to individual lobules within that lobe

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14
Q

tertiary branch of the mammory duct

A

intralobular ducts

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15
Q

intralobular ducts

A

the ducts within the lobule.\

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16
Q

secretory alveoli

A

terminal branches of mammory gland

17
Q

what is one unique feature of the breast

A

the secretory alveoli do not elaborate until pregnancy occurs

18
Q

nulligravida

A

never pregnant

19
Q

what makes the secondary and tertiary branches of the breast develop

A

-the influence of sex hormones during female puberty
- the breasts of males and children only contain the primary branches of ductal tissue

20
Q

label

A
21
Q

label

A
22
Q

what is this pointing to

A

secretory alveoli

23
Q

what is the epithelium of secretory alveoli

A

simple columar

24
Q

what is one way to diferentiate intralobular duct cells from secretory acini

A

ntralobular duct cells don’t contain Intracellular product so they are more coboidal

25
Q
A

top secretory alveoli
bottom intralobular duct

26
Q

what type of product is this

A

extracellular product

27
Q

what type of product is this?

A

intracellular product
pinching off of secretory alveoli

28
Q

what is this showing

A

ductal carcinoma in situ

29
Q

what is going on in these two picture

A

invasive ductal carinoma