last little bit after quiz 6 Flashcards
basal cell carcinomas
from keratinocytes of the stratum basale, special because of their stem-cell population
melanomas
from melanocytes
For a carcinoma to become malignant what must happen
cells involved must leave their layer of origin, and migrate into unfamiliar tissue
radial growth stage
proliferating cells are confined to the epidermis
vertical growth stage
proliferating cells have invaded the dermis (crossing tissue layers)
during what stage, radial or vertical growth, ado cancer cells recruit a blood supply
during the vertical growth stage, cancerous cells recruit a blood supply for themselves (angiogenesis) and become capable of spreading to distant sites (metastasis)
why do the cells have those white spaces between
cancer cells lack desmosomes and are motile
no cellular adhastion molecules between them
what is the line pointing to and what is it?
epithelial nest: cystic structures present In CT that
represent the immune system’s attempt to”wall off “migratory cancer
what cells are these and why are they brown
-macrophages In melanoma
-In melanoma the
Macrophages are brown because they have ingesting the melaocyes
what is the primary branch of the mammary glands
lactiferous duct
lactiferous duct
leads from the surface epithelium of the nipple to one lobe of the breast
what is the secondary branch of mammary glands
interlobular ducts
interlobular ducts
a duct that leads to individual lobules within that lobe
tertiary branch of the mammory duct
intralobular ducts
intralobular ducts
the ducts within the lobule.\
secretory alveoli
terminal branches of mammory gland
what is one unique feature of the breast
the secretory alveoli do not elaborate until pregnancy occurs
nulligravida
never pregnant
what makes the secondary and tertiary branches of the breast develop
-the influence of sex hormones during female puberty
- the breasts of males and children only contain the primary branches of ductal tissue
label
label
what is this pointing to
secretory alveoli
what is the epithelium of secretory alveoli
simple columar
what is one way to diferentiate intralobular duct cells from secretory acini
ntralobular duct cells don’t contain Intracellular product so they are more coboidal