[quiz 3] Flashcards
Which of the following is an antigenic lipid found in the phospholipid bilayer that covers the human cell?
cholesterol
beta-glucan
ergosterol
cardiolipin
Cardiolipin
Ankyrin-spectrin-brand3 of RBCs are an example of which protein membrane?
Integral
Which organelle is known to sequester calcium and is also known as the sarcoplasmic reticulum in muscles?
SER
Which organelle is the site of O-glycosylation of proteins
Golgi apparatus
T/F: the centrosome is a region composed solely of the cylindrical organelle composed mainly of a protein called tubulin in triplets
F
The ___ is made up of a pair of centrioles at its center, and is surrounded by pericentriolar material (PCM) that is important for microtubule nucleation
Centrosome
___ are a superfamily of related motor proteins that use a microtubule track in anterograde movement. They are vital to spindle formation during cell division in mitotic and meiotic chromosome separation
Kinesin
___ is a major intracellular degradation system during fasting that derives its degradative abilities from the ___
Autophagy
Lysosome
The pre-RNA and pre-tRNA are processed in the ___ and exits through ___
Nucleolus
Nuclear pore
___ are a family of basic proteins that associate with DNA in the nucleus and help condense it into chromatin
Histone
Which protein is responsible in release the positive supercoils that form during the unwinding of the DNA helix
DNA gyrase
A posttranslational processing and modification whereby newly synthesized proteins are combined with a carbohydrate moiety
Glycosylation
It refers to the initial RNA molecule synthesized, with length equivalent to the full length of the DNA transcribe
pre-mRNA or hnRNA
What part is spliced out in order to form the final useable form of your pre-mRNA?
introns
Which enzyme is found in the lagging strand but not in the leading strand in replication?
DNA ligase
What enzyme catalyzes the formation of polypeptide chains
Peptidyl transferase
In eukaryotic cells, the elongation step of transcription is performed by ___
RNA polymerase II
What is also known as RNA-dependent DNA polymerase and is found in viruses like HIV and the tips of telomeric regions of the DNA
Reverse transcriptase
What kind of RNA is involved in gene regulation, for example silencing some of the genes to avoid expression?
siRNA
In the generative cell cycle, the diploid (2N) configuration is seen in all the following stages except:
G0
G1
G2
G2
During this stage of the generative cell cycle, the cell continues the synthesis of RNA and new proteins. However, at this point, the cell has a tetraploid (4N) configuration
G2
In the generative cell cycle, this is considered to be the temporary resting period. No cell division occurs at this point and it has diploid (2N) configuration
G0
Which cell is terminal in G0 phase?
Liver cells
Cells of myocardium
Cells of seminiferous tubules post-radiation
Microglia in the brain
Cells of myocardium
The ___ is the portion of the chromosome to which proteins that will pull the sister chromatid apart attach
Kinetochore
Cohesin breakdown happens during ___
Anaphase
Actomyosin ring formation happens during ___
Telophase
The cell undergoing mitosis has a tetraploid (4N) chromosomal configuration in all these stages, except:
Prophase
Metaphase
Anaphase
Telophase
Telophase
At what stage of meiotic division does chromosome crossing over occur?
Prophase I
Enumerate the chromosome configuration in the nuclear division in meiosis
Bivalent chromosomes»_space; Sister chromatids»_space; Haploid chromosomes
In the pachytene stage, which create the genetic diversity?
Genetic recombination
The formation in prophase I that causes greater diversity in offspring
Diplotene
In human fetal oogenesis, all developing oocytes develop to this stage and are arrested in prophase I before birth. This is referred to as ___ and it lasts until meiosis is ___ to prepare oocyte for ovulation, which happens at puberty or even later
Dichtyotene
Resume
Which of the following is a mitogen?
E2F
RbP
p14
p53
E2F
Which of the following is a tumor suppressor gene?
MYC
p53
FGFR
MAPK
p53
If the ATM gene through the p53 protein cannot still repair massive double stranded breaks in the DNA, what processes will happen?
Bax gene triggers apoptosis