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CTGN 1st Shift > [quiz 3] > Flashcards

[quiz 3] Flashcards

1
Q

Which of the following is an antigenic lipid found in the phospholipid bilayer that covers the human cell?

cholesterol
beta-glucan
ergosterol
cardiolipin

A

Cardiolipin

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2
Q

Ankyrin-spectrin-brand3 of RBCs are an example of which protein membrane?

A

Integral

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3
Q

Which organelle is known to sequester calcium and is also known as the sarcoplasmic reticulum in muscles?

A

SER

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4
Q

Which organelle is the site of O-glycosylation of proteins

A

Golgi apparatus

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5
Q

T/F: the centrosome is a region composed solely of the cylindrical organelle composed mainly of a protein called tubulin in triplets

A

F

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6
Q

The ___ is made up of a pair of centrioles at its center, and is surrounded by pericentriolar material (PCM) that is important for microtubule nucleation

A

Centrosome

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7
Q

___ are a superfamily of related motor proteins that use a microtubule track in anterograde movement. They are vital to spindle formation during cell division in mitotic and meiotic chromosome separation

A

Kinesin

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8
Q

___ is a major intracellular degradation system during fasting that derives its degradative abilities from the ___

A

Autophagy
Lysosome

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9
Q

The pre-RNA and pre-tRNA are processed in the ___ and exits through ___

A

Nucleolus
Nuclear pore

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10
Q

___ are a family of basic proteins that associate with DNA in the nucleus and help condense it into chromatin

A

Histone

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11
Q

Which protein is responsible in release the positive supercoils that form during the unwinding of the DNA helix

A

DNA gyrase

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12
Q

A posttranslational processing and modification whereby newly synthesized proteins are combined with a carbohydrate moiety

A

Glycosylation

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13
Q

It refers to the initial RNA molecule synthesized, with length equivalent to the full length of the DNA transcribe

A

pre-mRNA or hnRNA

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14
Q

What part is spliced out in order to form the final useable form of your pre-mRNA?

A

introns

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15
Q

Which enzyme is found in the lagging strand but not in the leading strand in replication?

A

DNA ligase

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16
Q

What enzyme catalyzes the formation of polypeptide chains

A

Peptidyl transferase

17
Q

In eukaryotic cells, the elongation step of transcription is performed by ___

A

RNA polymerase II

18
Q

What is also known as RNA-dependent DNA polymerase and is found in viruses like HIV and the tips of telomeric regions of the DNA

A

Reverse transcriptase

19
Q

What kind of RNA is involved in gene regulation, for example silencing some of the genes to avoid expression?

A

siRNA

20
Q

In the generative cell cycle, the diploid (2N) configuration is seen in all the following stages except:

G0
G1
G2

A

G2

21
Q

During this stage of the generative cell cycle, the cell continues the synthesis of RNA and new proteins. However, at this point, the cell has a tetraploid (4N) configuration

A

G2

22
Q

In the generative cell cycle, this is considered to be the temporary resting period. No cell division occurs at this point and it has diploid (2N) configuration

A

G0

23
Q

Which cell is terminal in G0 phase?

Liver cells
Cells of myocardium
Cells of seminiferous tubules post-radiation
Microglia in the brain

A

Cells of myocardium

24
Q

The ___ is the portion of the chromosome to which proteins that will pull the sister chromatid apart attach

A

Kinetochore

25
Q

Cohesin breakdown happens during ___

A

Anaphase

26
Q

Actomyosin ring formation happens during ___

A

Telophase

27
Q

The cell undergoing mitosis has a tetraploid (4N) chromosomal configuration in all these stages, except:

Prophase
Metaphase
Anaphase
Telophase

A

Telophase

28
Q

At what stage of meiotic division does chromosome crossing over occur?

A

Prophase I

29
Q

Enumerate the chromosome configuration in the nuclear division in meiosis

A

Bivalent chromosomes&raquo_space; Sister chromatids&raquo_space; Haploid chromosomes

30
Q

In the pachytene stage, which create the genetic diversity?

A

Genetic recombination

31
Q

The formation in prophase I that causes greater diversity in offspring

A

Diplotene

32
Q

In human fetal oogenesis, all developing oocytes develop to this stage and are arrested in prophase I before birth. This is referred to as ___ and it lasts until meiosis is ___ to prepare oocyte for ovulation, which happens at puberty or even later

A

Dichtyotene
Resume

33
Q

Which of the following is a mitogen?

E2F
RbP
p14
p53

A

E2F

34
Q

Which of the following is a tumor suppressor gene?

MYC
p53
FGFR
MAPK

A

p53

35
Q

If the ATM gene through the p53 protein cannot still repair massive double stranded breaks in the DNA, what processes will happen?

A

Bax gene triggers apoptosis

36
Q
A

CTGN 1st Shift (8 decks)

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