Quiz 2 PATH Clinical

Question 1

62 y/o man w/ easy bruising and recurrent nosebleeds over 4 months. Weakness, Weightless Mucosal pallor and bruising on upper and lower extremities in various stages of healing. Splenomegaly, Anemia and thrombocytopenia,
Bone Marrow Biopsy: TRAP(+)

Answer 1

Hairy Cell Leukemia

Question 2

32 y/o woman w/ low-grade fever, night sweats, fatigues for 2 months. Non-tender cervical and supraclavicular lymphadenopathy

Answer 2

Nodular Sclerosis Hodgkin Lymphoma aka lacunar cell variant

Question 3

9 y/o boy w/ fever Hx of otitis media, mild lymphadenopathy, 4 cm osteolytic lesion in mastoid bone, s100+, CD1a+

Answer 3

Langerhans Cell Histiocytosis

Question 4

75 y/o man w/ fatigue and decreased urine output for 1 week. Ibuprofen as needed for back pain, constipation, tenderness over L Spine, pedal edema, Hb = 8.7, Creatinine = 2.3, Calcium = 12.6

Answer 4

Multiple Myeloma