Quiz #2 Flashcards

1
Q

All of the following are cell responses to stress except for:

  1. Adaptation
  2. Death
  3. Wound Healing
  4. Nutritional Imbalance
A

Nutritional Imbalance

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2
Q

Which of the following forms of adaptation signifies the replacement of a normal adult cell with another cell type?

  1. Hypertrophy
  2. Metaplasia
  3. Neoplasia
  4. Dysplasia
A

Metaplasia

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3
Q

There is no direct correlation between metaplasia and cancer:

  1. True
  2. False
A

True

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4
Q

Ischemia is most often seen with:

  1. Artherosclerosis
  2. Osteoporosis
  3. Arthritis
  4. Sickle Cell Anemia
A

Artherosclerosis- build up of plaque in arteries

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5
Q

Hypoxia occurs more often than ischemia:

  1. True
  2. False
A

False

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6
Q

Which of the following is not a way in which cell injury occurs:

  1. Free radical formation
  2. Inducing hypoxia and decreased pH
  3. Hypertrophy
  4. Impairing Ca2+ homeostasis
A

Hypertrophy

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7
Q

Synonym for necrosis?

A

Infarct

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8
Q

Which of the following types of necrosis occurs as a result of hypoxemia?

  1. Caseous
  2. Coagulative
  3. Liquefactive
A

Coagulative (more common)

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9
Q

Which of the following forms of necrosis is caused from bacterial or fungal infection, most often with tuberculosis?

  1. Caseous
  2. Coagulative
  3. Liquefactive
A

Caseous

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10
Q

How does apoptosis differ from necrosis?

A

Apoptosis is a highly regulated and controlled process

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11
Q

_________necrosis can occur as a result of__________necrosis?

  1. Coagulative; Caseous
  2. Caseous; liquefactive
  3. Liquefactive; Caseous
  4. Liquefactive; Coagulative
A

Liquefactive; Coagulative

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12
Q

Liquefactive necrosis can occur in:

  1. Calcium rich tissue
  2. Lipid rich tissue
  3. Carbohydrate rich tissue
  4. Vitamin D rich tissue
A

Lipid rich tissue

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13
Q

All of the following can occur during coagulative necrosis in the heart except:

  1. Vasodilation of arteries
  2. Nuclei being lost
  3. structural loss of cytoplasm
  4. No clear striations
A

Vasodilation of arteries

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14
Q

Gangrene is necrosis of a small mass:

  1. True
  2. False
A

False- it is necrosis of a large mass

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15
Q

Which of the following results from Iscehmia?

  1. Dry Gangrene
  2. Wet Gangrene
  3. Caseous Necrosis
A

Dry Gangrene

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16
Q

Which of the following affects both arterial and venous outflow supply?

  1. Dry Gangrene
  2. Wet Gangrene
A

Wet Gangrene

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17
Q

Which of the following tissue types conducts the specific functions of the organ it is contained within?

  1. Mesenchymal Tissue
  2. Connective Tissue (Stroma)
  3. Parenchymal Tissue
  4. Adipose Tissue
A

Parenchymal

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18
Q

In 1st intention (primary) wound healing, there is no tissue loss:

  1. True
  2. False
A

True

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19
Q

Collagen synthesis during the proliferative phase peaks b/w:

  1. 2-3 days
  2. 5-7 Days
  3. 8-10 Days
  4. 2 weeks
A

5-7 Days

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20
Q

Cytokines, small molecules used for signaling mechanisms are most often seen in which healing phase:

  1. Inflammatory
  2. Proliferative
  3. Remodeling
A

Proliferative

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21
Q

What is the final step of the Proliferative Phase?

  1. Collagen synthesis
  2. Angiogenesis
  3. Epithelialization
  4. Formation of granulation tissue containing capillary buds and vascularized tissue
A

Epithelialization- the scab falls off!

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22
Q

Scar Massage is most common in which stage?

  1. Inflammatory
  2. Proliferative
  3. Remodeling
A

Remodeling

23
Q

Skin has what percentage of strength after sutures have been removed?

  1. 70%
  2. 10%
  3. 80%
  4. 30%
A

10% (5-7 days after sutures have been removed)

24
Q

With tears and ruptures occurring in ligaments, 80% percent of the normal tensile strength is regained by:

  1. The 5 week
  2. 6 months
  3. 1 year
  4. 1-3 years
A

1 year

25
Q

With the presence of an infection, a wound is not typically healed:

  1. True
  2. False
A

True

26
Q

Most cells are not actively mitotic:

  1. True
  2. False
A

True

27
Q

How are stem or blast cells different from normal cells

A

Stem/blast cells produce their own types of cells as well as other types

28
Q

Which of the following are true about the cell cycle:

  1. S phase occurs after G1
  2. S Phase occurs after G2
  3. Mitosis immediately follows the S phase
  4. Mitosis occurs before the S phase
A

S phase occurs after G1

29
Q

Neoplasm is associated with:

  1. Tumor
  2. Malignancy
  3. Cancer
A

Tumor

30
Q

Schwannoma occurs in all of the following places except:

  1. Peripheral Nerves
  2. Spinal Cord
  3. Heart
  4. CNS
A

Heart. It is benign.

31
Q

Osteronoma is not benign

  1. True
  2. False
A

False

32
Q

Cancer of connective tissue is known as:

  1. Carcinoma
  2. Sarcoma
  3. Leukemia
  4. Lymphoma
A

Sarcoma. It is not as common but it is malignant

33
Q

A high portion of regeneration in epithelial tissue and chemical exposure or radiation leads to:

  1. Carcinoma
  2. Sarcoma
  3. Leukemia
  4. Lymphoma
A

Carcinoma

34
Q

Leukemia and Lymphoma fall under:

  1. Carcinoma
  2. Sarcoma
  3. Hematologic
A

Hematologic

35
Q

Pap tests, occult blood, imaging, and tumor markers are all used for:

  1. Cancer Screening
  2. Diagnostic Pathology
  3. Prognostic Factors
  4. Staging
A

Cancer Screening

36
Q

Tissue samples are required to make a diagnosis

  1. True
  2. False
A

True

37
Q

What is the gold standard for diagnosis?

A

Pathology

38
Q

Injection of a dye to locate pathology occurs with:

  1. Triple Test
  2. Surgical pathology
  3. Fine needle aspirates
  4. Biopsy
A

Surgical pathology ( sentinel nodes, lymph nodes, breast cancer)

39
Q

Which is the most important prognostic factor?

  1. Stage
  2. Cell type
  3. Grade
  4. Performance Status
A

Stage

40
Q

Which can indicate how aggressive a cancer is and how fast will it spread?

  1. Stage
  2. Cell type
  3. Grade
  4. Performance Status
A

Grade

41
Q

The Karnofsky scale and the ECOG scale is relative to cancer________

  1. Stage
  2. Grade
  3. Performance Status
A

Performance Status

42
Q

Grading is based on a scale of _______

  1. 1-4
  2. 0-4
  3. 0-5
A

1-4

43
Q

A cancer patient who undergoes limited self care and is in a bed for more than half of waking hours is probably at a performance status of

  1. 2
  2. 3
  3. 4
  4. 5
A

3

44
Q

Beginning at what stage is the basement membrane no longer in-tact:

  1. 0
  2. 1
  3. 2
  4. 3
A

1

45
Q
At what stage is it CERTAIN that cancer has spread outside affected tissue
1
2
3
4
A

3

46
Q

Which staging scale of the TNM system is binary (0-1)?

  1. Tumor
  2. Nodes
  3. Metastasis
A

Metastasis. The others are scaled 0-4

47
Q

Which of the following is not a tumor suppressor associated with a solid cancer :

  1. BRCA1
  2. BRCA2
  3. C-ab1
  4. P53
A

C-ab1

48
Q

Concomitant therapy is also known as what treatment sequence:

  1. Primary
  2. Adjuvent
  3. Salvage
  4. Palliative
A

Adjuvent

49
Q

Which treatment does one go through with the recurrence of cancer?

  1. Primary
  2. Adjuvent
  3. Salvage
  4. Palliative
A

Salvage

50
Q

Surgery is optimal for higher staged cancers:

  1. True
  2. False
A

False. Surgery can be used for metastatic cancer but it depends.

51
Q

Brachytherapy is a form of:

  1. Radiation therapy
  2. Chemotherapy
A

Radiation therapy

52
Q

For a patient with Hodgkin’s lymphoma, they will most likely undergo

  1. Surgery
  2. Chemotherapy
  3. Radiation Therapy
  4. Targeted Therapy
A

Radiation therapy

53
Q

Monoclonal antibodies are used in:

  1. radiation therapy
  2. targeted therapy
  3. Chemotherapy
  4. surgery
A

targeted therapy