Quiz 1/ Practical Flashcards
the primary formed element of the blood; biconcave disc-shaped cell that transports oxygen and carbon dioxide on its hemoglobin molecules
erythrocyte
a class formed elements of blood that perform functions relating to the immune system
leukocyte
contain cytoplasmic granules that the cells release when activated
granulocytes
lack visible cytoplasmic granules
agranulocytes
- nucleus has 3-5 lobes
* cytoplasmic granules are not visible
neutrophil
- nucleus is bilobed
* cytoplasmic granules stain red
eosinophil
- nucleus is S-shaped
* cytoplasmic granules stain dark purple
basophil
which classes/types of leukocytes are considered to be granulocytes?
- neutrophil
- eosinophil
- basophil
- nucleus is spherical
* thin rim of light blue cytoplasm becomes visible when cell is stained
lymphocyte
- nucleus is U-shaped
* light blue to purple cytoplasm
monocyte
which classes/types of leukocytes are considered to be agranulocytes?
- lymphocyte
* monocyte
- most common type of leukocyte making up 60-70% of total leukocytes in blood
- attracted to injured cells
- directly kill bacteria by phagocytosis
neutrophils
- this leukocyte only accounts for less than 4% of total leukocytes in blood
- involved in the body’s response to infection with parasitic worms and in allergic reactions
eosinophils
- least common leukocyte
- makes up less than 1% of total leukocytes in the blood
- release chemicals from their granules that mediate inflammation
basophils
- second most numerous type of leukocyte
- makes up to 20-25% of total leukocytes of blood
- contain two basic types that are activated by cellular markers called antigens
lymphocytes
- the largest leukocytes
- accounts for 3-8% of the total leukocyte population
- some mature into very active phagocytes called macrophages
monocytes
- smallest of the formed elements
- involved in hemostasis
- not true cells, small fragments of cells surrounded by a plasma membrane
- lack nuclei
platelets
the cells and cell fragments suspended into the plasma
formed elements
what are the three types of formed elements found in blood?
erythrocytes
leukocytes
platelets
a protein with four polypeptide subunits, each associated with a iron-containing heme group
hemoglobin
what is the order of development of an erythrocyte?
hematopoietic stem cell -> proerythroblast -> erythroblast -> reticulocyte -> erythrocyte
old and damaged erythrocytes are destroyed in this organ?
spleen
stoppage of blood loss from an injured vessel
hemostasis
a collections of platelets, clotting proteins, and other formed elements
blood clot
what are the phases of hemostasis?
vascular spasm platelet plug formation coagulation clot retraction thrombolysis
what are the two major groups of erythrocyte antigens?
ABO and Rh group
what is blood typing based on?
the presence or absence of antigens from the ABO and Rh groups
what are the three type of antibodies found in blood?
A- antibodies
B- antibodies
Rh- antibodies
how is blood type determined?
by treating erythrocytes with antibodies and watching for agglutination reactions
which blood type is the universal donor?
Type- O
lack antigens of the ABO and Rh groups
which blood type is the universal recipient?
Type AB+
lacks anti A, anti B, and anti-Rh antibodies
decreased oxygen-carrying capacity of blood
Anemia
two-sided pump that drives blood into the blood vessels
heart
where does the atria receive and pump blood?
the atria receive blood from the veins and pump blood into the ventricles
where does the ventricles pump blood?
the ventriclespump blood into the arteries
what is the function of the right side of the heart?
pulmonary pump that pumps deoxygenated blood through the vessels of the pulmonary circuit
what is the function of the left side of the heart?
systemic pump that drives oxygenated blood through the systemic circuit
what are the three layers of the heart wall?
pericardium
myocardium
endocardium
what are the two layers of the pericardium?
fibrous pericardium
serous pericardium
what are the two layers of the serous pericardium?
parietal pericardium
visceral pericardium
what is the serous fluid layer called between the parietal and visceral pericardium?
pericardial cavity
consists of the coronary arteries, which supply the myocardium with blood, and the coronary vein, which drain the myocardium
coronary circulation
what are the main two branches of the left coronary artery?
anterior interventricular artery
circumflex artery
the large vessel that receives blood from the coronary veins and empties it into the right atrium
coronary sinus
what are the 3 veins that the coronary sinus receives blood from?
great cardiac vein
middle cardiac vein
small cardiac vein
what are the 4 main great vessels?
- venae cavae “(superior & inferior)
- pulmonary trunk
- pulmonary veins
- aorta
what are the 2 atria separated by?
interatrial septum
what are the 2 ventricles separated by?
interventricular septum
why is the left ventricle wall thicker than the right ventricle?
pumps against higher pressure
blood flowing into the ventricles passes through which valves?
tricuspid valve
mitral valve
blood flowing out of the ventricles passes through what 2 valves?
aortic valve
pulmonary valve
the structure that joins the aorta and pulmonary trunk?
ligamentum arteriosum
- upper chamber of the heart
- receives blood from the superior and inferior vena cava and coronary sinus
- sends the blood to the right ventricle
right atrium
- upper chamber of the heart
- receives blood from the pulmonary veins
- sends the blood to the left ventricle
left atrium
flap-like extension that expands to increase the volume blood the atrium may hold
auricle
- lower chamber of the heart
- receives blood from the right atrium
- sends blood to the pulmonary trunk
right ventricle
- lower chamber of the heart
- receives blood from the left atrium
- sends blood to the aorta
left ventricle
- carries deoxygenated blood to the right atrium
* drains upper regions of the body
superior vena cana
- carries deoxygenated blood to the left atrium
* drains lower regions of the body
inferior vena cava
*carries oxygenated blood to the systemic arteries *receives from the left ventricle
aorta
- carries oxygenated blood from right lung
* delivers to left atrium
right pulmonary veins
- carries oxygenated blood from the left lung
* delivers to left atrium
left pulmonary veins
- carries deoxygenated blood to the pulmonary arteries
* receives from the right ventricle
pulmonary trunk
- arises from right side of aorta
- occupies coronary sulcus
- small branches supply right atrium
- divides into posterior interventricular artery and marginal arteries
right coronary artery
- arises from left side of aorta
- passes posterior to pulmonary trunk
- divides into anterior interventricular artery and circumflex artery
left coronary artery
- branch of coronary artery
- occupies posterior coronary sulcus
- supplies left atrium and posterior left ventricle
circumflex artery
- branch of left coronary artery
- occupies anterior interventricular sulcus
- supplies left ventricle and interventricular septum
anterior interventricular artery
- occupies anterior interventricular sulcus
- drains left ventricle and interventricular septum
- empties into coronary sinus
great cardiac vein
- an enlarged vein
- occupies posterior part of coronary sulcus
- drains blood from cardiac veins
- empties into the right atrium
coronary sinus
- occupies posterior interventricular sulcus
- drains distal areas of both ventricles
- empties into the coronary sinus
middle cardiac vein
- branch of right coronary artery
- occupies posterior interventricular sulcus
- supplies distal areas of both ventricles
posterior interventricular artery
prevents backflow into right ventricle during ventricular relaxation
pulmonary valve
prevents backflow into the left ventricle during ventricular relaxation
aortic valve
prevents backflow into the right atrium during ventricular contraction
tricuspid valve
prevents backflow into the left atrium during ventricular contraction
bicuspid valve
list the path of blood flow in pulmonary circulation
venules -> veins -> superior and inferior vena ->
right atrium -> tricuspid valve -> right ventricle -> pulmonary valve -> pulmonary trunk -> pulmonary arteries -> lungs
list the path of blood flow in systemic circulation
pulmonary veins -> left atrium -> bicuspid valve -> left ventricle -> aortic valve -> aorta -> arteries -> arterioles -> capillaries-> rest of body
cells that contract in response to action potentials via the sliding-filament mechanism
cardiac muscle cells
non contractile and nonstriated cardiac muscle cells that are autorhythmic and spontaneously generate action potentiaks
pacemaker cells
- influx of calcium ions as potassium ions exit
- lengthens the action potential
- lengthens and strengthens the hearts contraction
- lengthens the refractory period
plateau phase
pacemaker of the heart (paces the heart at 60 or more beats per minute)
Sinoatrial node
paces the heart at 40 beats per minute
atrioventricular node
the purkinje system consists of?
AV bundle
Right and left bundle branches
Purkinje fibers
measures the electrical changes in the heart
electrocardiogram
describes the physiology of cardiac pumping
mechanical physiology
heart sound caused by the closing of the AV valves at the beginning of isovolumetric contraction
S1
heart sound caused by the closing of the semilunar vales at the beginning of isovolumetric relaxation
S2
what are the four stages of the cardiac cycle?
ventricular filling
isovolumetric contraction
ventricular ejection
isovolumetric relaxation
the volume of blood in the ventricles after atrial systole
end-diastolic volume (EDV)
the blood remaining in the ventricles
end- systolic volume (ESV)
blood drains from the atria to the ventricles
ventricular filling
both valves are shut and ventricular volume remains constant
isovolumetric contraction
- when pressure in the ventricles rise above the pressure in the pulmonary trunk and aorta
- blood ejected from the ventricles through the semilunar valves
ventricular ejection
- when the ventricles re-enter diastole
- both sets of valves are closed
- volume in the ventricles remains constant
isovolumetric relaxation
wave that represents atrial depolarization
P wave
wave that represents ventricular depolarization
QRS complex
wave that represents ventricular repolarization
T wave
wave that represents the entire duration of a cardiac action potential
R-R interval
the wave that represents the duration of atrial repolarization and AV node delay
P-R interval
the wave that represents the entire duration of a ventricular action potential
Q-T interval
the wave that represents ventricular plateau phase
S-T sement
what are the 3 types of arteries that the pulmonary and systemic circuits consists of?
- Arteries
- Veins
- Capillaries
what are the 3 tissue layers of a blood vessel?
- tunic intima
- tunic media
- tunic externa
the inner most layer of the blood vessel composed of endothelium and its basal lamina, a thin layer of connective tissue, and internal elastic lamina
tunic intima
middle layer of the blood vessel composed of smooth muscle cells and the external elastic lamina
tunic media
outermost layer of the blood vessel composed of supportive connective tissue
tunic externa
what are the 3 main types of arteries?
- elastic arteries
- muscular arteries
- arterioles
arteries that are closest to the heart and have an extensive elastic laminae
Elastic arteries
arteries that are intermediate in diameter and deliver blood to organs
muscular arteries
smallest diameter arteries that control blood flow to tissues
arterioles
receptors that monitor blood pressure
baroreceptors
smallest veins that drain capillary beds
venules
what are the 3 types of anastomoses?
arterial
venous
arteriovenous
study of blood flow in the cardiovascular system
hemodynamics
the force that blood exerts on the walls of the blood vessels
blood pressure
the volume of blood that flows through the systemic and pulmonary circuit in a minute
bloof flow
impedance to blood flood
resistance
what are the 3 factors that determine blood pressure?
resistance
cardiac ouput
blood volume
the volume of blood pumped into the pulmonary and systemic circiuis in one minute
cardiac output
the sequence of mechanical events in the heart that takes place from one heartbeat to the next
cardiac cycle
this pressure is 95mm Hg
mean arterial pressure (MAP)
this pressure is 120mm Hg
systolic pressuree
this pressure is 80mm Hg
diastolic pressure
the difference in the systolic and diastolic pressures (35mm Hg)
pulse pressure
how is MAP calculated?
by adding 1/3 of the pulse pressure to the diastolic pressure
what is arterial blood pressure measure with?
sphygmomanometer
what causes vasoconstriction of the blood vessels?
sympathetic nervous system releasing epinephrine or norepinephrine
what causes vasodilation of the blood vessels?
parasympathetic nervous system releasing acetylcholine
high blood pressure (systolic pressure over 140mm Hg and diastolic pressure over 90mm Hg)
hypertension
low blood pressure (systolic pressure under 90mm Hg and diastolic pressure under 60mm Hg)
hypotension
the blood flow through a capillary bed to a tissue
tissue perfusion
what are the three types of capillaries?
continuous capillaries
fenestrated capillaries
sinusoidal capillaries
a types of capillary joined by tight junctions, and therefore not leaky
continuous capillaries
a type of capillary that contains fenestrations that makes them leakier than continuous capillaries
fenestrated capillaries
a type of capillary that have large pores and their endothelium cells makes them extremely leaky
sinusoidal capillaries
pressure caused by the force that the blood exerts on the wall of a blood vessel
hydrostatic pressure
pressure caused by solutes particles in a solution exert a force on water molecules
osmotic pressure
pressure caused by osmotic pressure being higher in the blood than in the interstitial fluid
colloid osmotic pressure
the pressure thats the difference between the opposing forces of the hydrostatic pressure gradient and the colloid osmotic pressure
net filtration pressure
caused by an excessive amount of water in the interstitial fluid
edema
what are the four divisions of the aorta?
ascendind aorta
aorticarch
descending thoracic aorta
descending abdominal aorta
what are the 3 branches of the aorta?
brachiocephalic artery
left common carotid artery
left subclavian artery
what does the common iliac arteries divide into?
internal (supply pelvis)and external (supply lower limb) iliac arteries
arteries that supply the superficial head and face
external carotid arteries
arteries that supply blood to the brain stems
internal carotid arteries and vertebral arteries
trunk that supplies the liver, pancreas, duodenum, stomach, and spleen
celiac trunk
an artery that supplies the small intestine and much of the large intesine
superior mesenteric artery
arteries that supplies the kidneys
renal arteries
supplies the remainder of the large intestine
inferior mesenteric artery
supplies the upper limb and branches to become the axillary artery and the brachial artery
subclavian artery
artery that splits into the radial and ulnar areteries
brachial artey
becomes the femoral artery
external iliac artery
becomes the popliteal artery
femoral artery
splits into the anterior tibial artery (becomes the dorsalis pedalis) and the posterior tibial artery
popliteal artery
blood from the head and neck drains into what vein?
external jugular vein, internal jugular vein, vertebral veins
blood from the brain drains into what sinus?
dural sinuses
blood from the anterior thoracic and abdominal walls drain
internal thoracic veins
blood from the posterior thoracic and abdominal walls drain
azygos system
what veins drain into the inferior vena cava?
gonadal, renal and hepatic veins
what veins drain into the hepatic portal vein
splenic, gastric, superior and inferior mesenteric veins
the upper limb is drained by which superficial and deep veins?
(superficial) cephalic vein, meddial antebrachial vein, basilic vein. (deep) radial and ulnar veins, brachial vein, axillary, and subclavian vein
the lower limb is drained by which superficial and deep veins?
(superficial) great and small saphenous veins. (deep) anterior and posterior tibial veins, popliteal vein, and femoral vein