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Systems Pathology 2 > Quiz 1 > Flashcards

Quiz 1 Flashcards

1
Q

Layers of the epidermis(deep to superficial)

A

stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, stratum corneum
(big spenders grab loose change)
pg 5

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2
Q

macule

A

flat discoloration

pg 9

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3
Q

papule

A

elevated dome

pg 9

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4
Q

plaque

A

flat-topped elevation

pg 9

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5
Q

scale

A

dry, horny, plate-like growth

pg 9

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6
Q

vesicle

A

fluid-filled area (<5mm)

pg 9

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7
Q

wheal

A

raised area of edema (hive)

pg 9

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8
Q

acantholysis

A

loss of keratinocyte adhesion

pg 12

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9
Q

acanthosis

A

epidermal hyperplasia

pg 12

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10
Q

hyperkeratosis

A

hyperplasia of the stratum corneum

pg 12

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11
Q

spongiosis

A

intracellular epidermal edema

pg 12

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12
Q

4 Acute Inflammatory Dermatoses

A

1) urticaria
2) acute eczematous dermatitis
3) erythema multiform
4) acne
pg 13

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13
Q

Condition presenting with red rounded papules that itch

A

urticaria

pg 15

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14
Q

Urticaria is a type __ hypersensitivity

A

type I

pg 15

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15
Q

What is the common age group affected by urticaria?

A

20-40 years

pg 16

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16
Q

Subtype of urticaria presenting with DERMAL edema following excessive complement activation

A

Hereditary Angioedema

pg 19

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17
Q

Hereditary Angioedema is caused by what inherited deficiency?

A

C1 esterase inhibitor

pg 19

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18
Q

“Proper” term for eczema`

A

Acute eczematous dermatitis

pg 21

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19
Q

What type(s) of hypersensitivities are associated with eczema?

A 
type I (allergic)
type IV (delayed)
pg 23
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20
Q

Most common form of eczema?

A

allergic contact dermatitis

pg 25

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21
Q

Allergic contact dermatitis is which type of hypersensitivity?

A

type IV

pg 24

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22
Q

Atopic dermatitis is which type of hypersensitivity?

A

type I

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23
Q

Type of eczema associated with a genetic risk

A

atopic dermatitis

pg 26

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24
Q

Atopic Triad

A

1) dermatitis
2) asthma
3) rhinitis
pg 26

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25
Q

Common onset of atopic dermatitis

A

childhood

pg 26

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26
Q

Condition presenting with “targetoid” skin lesions

A

erythema multiforme

pg 30

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27
Q

Erythema multiforme is often mistaking for what other condition?

A

ringworm

28
Q

Erythema multiforme is a type __ hypersensitivity

A

type IV

pg 31

29
Q

Two types of erythema multiforme

A

1) minor
2) major
pg 33

30
Q

Which type of erythema multiforme typically occurs post infection?

A

minor

pg 33

31
Q

Which type of erythema multiforme is life-threatening?

A

major

pg 33

32
Q

Special name given to erythema multiforme major when covering <30% of the body

A

Stevens-Johnson Syndrome

pg 34

33
Q

Special name given to erythema multiforme major when covering >30% of the body

A

Toxic Epidermal Necrolysis

pg 34

34
Q

Common form of acne

A 
acne vulgaris (80% pop.)
pg 37
35
Q

When are males more likely to get acne?

A

adolescence

pg 37

36
Q

when are females more likely to get acne?

A

adulthood

pg 37

37
Q

More severe form of acne

A

cystic acne

pg 38

38
Q

When is baby acne most likely to occur?

A

2 months

pg 40

39
Q

How common is baby acne?

A

20% of babies; 1:5

pg 40

40
Q

milium

A

keratin-filled cysts

pg 40

41
Q

3 Chronic Inflammatory Dermatoses

A

1) psoriasis
2) lichen planus
3) lichen simplex chronicus
pg 42

42
Q

Autoimmune skin condition with itchy epidermal hyperplasia

A

psoriasis

pg 44

43
Q

how common is psoriasis?

A

2% pop.

pg 44

44
Q

Describe a psoriasis lesion

A

well-demarcated, pink-to-salmon colored plaque, covered by a flaky silver-white scale
pg 45

45
Q

Common locations of psoriasis

A

elbows, knees, scalp, lumbosacral region

pg 45

46
Q

Common treatments for psoriasis

A

methotrexate, cyclosporine, phototherapy (UVB)

pg 45

47
Q

small micro bleeds are the site of psoriasis lesions

A

Auspitz sign

pg 48

48
Q

Psoriasis of the nail beds is often mistaken for what?

A

a fungal infection

pg 48

49
Q

Psoriasis plaque formation on a site of prior trauma

A

koebner phenomenon

pg 50

50
Q

Psoriatic arthritis occurs in __-__% of patients

A

5-30%

pg 51

51
Q

Psoriatic arthritis is often described as a ____ deformity

A

pencil-in-cup

pg 51

52
Q

Technical term for “sausage digits”

A

dactylitis

pg 53

53
Q

dactylitis occurs in __% of psoriasis patients

A

35%

pg 53

54
Q

Autoimmune skin condition involving t cells at the dermoepidermal junction

A

lichen planus

pg 56

55
Q

Common age group affected by lichen planus

A

middle-aged adults

pg 57

56
Q

Most common location of lichen planus

A

symmetrical on extremities

pg 57

57
Q

6 P’s of lichen planus

A

1) pruritic (itchy)
2) purple
3) polygonal
4) planar
5) papules
6) plaque
pg 57

58
Q

white mesh pattern associated with lichen planus often found in mouth

A

Wickham’s striae

pg 58

59
Q

__% of lichen planus patients have oral involvement

A

70%

pg 58

60
Q

Condition due to repetitive trauma leading to epidermal hyperplasia & dermal scarring

A

lichen simplex chronicus

pg 60

61
Q

Asymptomatic hyperpigmentation of skin

A

acanthosis nigricans

pg 63

62
Q

Common locations of acanthosis nigricans

A

body fold/creases (axillae, groin, neck)

pg 63

63
Q

Risks associated with acanthosis nigricans

A

diabetes, obesity, cancer genetics

pg 63

64
Q

Red rash with honey-colored crust

A

impetigo

pg 67

65
Q

Most common cause of impetigo

A

staph. aureus

pg 67

66
Q

Deeper bacterial skin infection

A

dermal abscess

pg 70

67
Q

common cause of dermal abscess

A

pseudomonas aeruginosa

pg 70

Systems Pathology 2 (8 decks)

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