Quiz 1 Flashcards
Layers of the epidermis(deep to superficial)
stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, stratum corneum
(big spenders grab loose change)
pg 5
macule
flat discoloration
pg 9
papule
elevated dome
pg 9
plaque
flat-topped elevation
pg 9
scale
dry, horny, plate-like growth
pg 9
vesicle
fluid-filled area (<5mm)
pg 9
wheal
raised area of edema (hive)
pg 9
acantholysis
loss of keratinocyte adhesion
pg 12
acanthosis
epidermal hyperplasia
pg 12
hyperkeratosis
hyperplasia of the stratum corneum
pg 12
spongiosis
intracellular epidermal edema
pg 12
4 Acute Inflammatory Dermatoses
1) urticaria
2) acute eczematous dermatitis
3) erythema multiform
4) acne
pg 13
Condition presenting with red rounded papules that itch
urticaria
pg 15
Urticaria is a type __ hypersensitivity
type I
pg 15
What is the common age group affected by urticaria?
20-40 years
pg 16
Subtype of urticaria presenting with DERMAL edema following excessive complement activation
Hereditary Angioedema
pg 19
Hereditary Angioedema is caused by what inherited deficiency?
C1 esterase inhibitor
pg 19
“Proper” term for eczema`
Acute eczematous dermatitis
pg 21
What type(s) of hypersensitivities are associated with eczema?
type I (allergic) type IV (delayed) pg 23
Most common form of eczema?
allergic contact dermatitis
pg 25
Allergic contact dermatitis is which type of hypersensitivity?
type IV
pg 24
Atopic dermatitis is which type of hypersensitivity?
type I
Type of eczema associated with a genetic risk
atopic dermatitis
pg 26
Atopic Triad
1) dermatitis
2) asthma
3) rhinitis
pg 26
Common onset of atopic dermatitis
childhood
pg 26
Condition presenting with “targetoid” skin lesions
erythema multiforme
pg 30
Erythema multiforme is often mistaking for what other condition?
ringworm
Erythema multiforme is a type __ hypersensitivity
type IV
pg 31
Two types of erythema multiforme
1) minor
2) major
pg 33
Which type of erythema multiforme typically occurs post infection?
minor
pg 33
Which type of erythema multiforme is life-threatening?
major
pg 33
Special name given to erythema multiforme major when covering <30% of the body
Stevens-Johnson Syndrome
pg 34
Special name given to erythema multiforme major when covering >30% of the body
Toxic Epidermal Necrolysis
pg 34
Common form of acne
acne vulgaris (80% pop.) pg 37
When are males more likely to get acne?
adolescence
pg 37
when are females more likely to get acne?
adulthood
pg 37
More severe form of acne
cystic acne
pg 38
When is baby acne most likely to occur?
2 months
pg 40
How common is baby acne?
20% of babies; 1:5
pg 40
milium
keratin-filled cysts
pg 40
3 Chronic Inflammatory Dermatoses
1) psoriasis
2) lichen planus
3) lichen simplex chronicus
pg 42
Autoimmune skin condition with itchy epidermal hyperplasia
psoriasis
pg 44
how common is psoriasis?
2% pop.
pg 44
Describe a psoriasis lesion
well-demarcated, pink-to-salmon colored plaque, covered by a flaky silver-white scale
pg 45
Common locations of psoriasis
elbows, knees, scalp, lumbosacral region
pg 45
Common treatments for psoriasis
methotrexate, cyclosporine, phototherapy (UVB)
pg 45
small micro bleeds are the site of psoriasis lesions
Auspitz sign
pg 48
Psoriasis of the nail beds is often mistaken for what?
a fungal infection
pg 48
Psoriasis plaque formation on a site of prior trauma
koebner phenomenon
pg 50
Psoriatic arthritis occurs in __-__% of patients
5-30%
pg 51
Psoriatic arthritis is often described as a ____ deformity
pencil-in-cup
pg 51
Technical term for “sausage digits”
dactylitis
pg 53
dactylitis occurs in __% of psoriasis patients
35%
pg 53
Autoimmune skin condition involving t cells at the dermoepidermal junction
lichen planus
pg 56
Common age group affected by lichen planus
middle-aged adults
pg 57
Most common location of lichen planus
symmetrical on extremities
pg 57
6 P’s of lichen planus
1) pruritic (itchy)
2) purple
3) polygonal
4) planar
5) papules
6) plaque
pg 57
white mesh pattern associated with lichen planus often found in mouth
Wickham’s striae
pg 58
__% of lichen planus patients have oral involvement
70%
pg 58
Condition due to repetitive trauma leading to epidermal hyperplasia & dermal scarring
lichen simplex chronicus
pg 60
Asymptomatic hyperpigmentation of skin
acanthosis nigricans
pg 63
Common locations of acanthosis nigricans
body fold/creases (axillae, groin, neck)
pg 63
Risks associated with acanthosis nigricans
diabetes, obesity, cancer genetics
pg 63
Red rash with honey-colored crust
impetigo
pg 67
Most common cause of impetigo
staph. aureus
pg 67
Deeper bacterial skin infection
dermal abscess
pg 70
common cause of dermal abscess
pseudomonas aeruginosa
pg 70
