Quiz 1 Flashcards
All the following are characteristics of acute-phase reactants EXCEPT:
-they limit destruction of host tissue
-they are constituents that increase rapidly in response to infection
-they enhance phagocytosis
-they are used to diagnose a specific disease
they are used to diagnose a specific disease
the test that could be used to determine whether a patient has a specific deficiency in C3.s
Radial immunodiffusion
Which of the following can activate the alternative complement pathway?
-IgG
-C1q
-mannose-binding lectin
-C3b
C3b
Which of the following is a characteristic of opsonins?
-They are expressed on the surface of neutrophils
-They are molecules that coat bacteria, making them more susceptible to phagocytosis
-They are produced by NK cells
-They are carbohydrates that stimulate T cells
-They are molecules that coat bacteria, making them more susceptible to phagocytosis
Where does the specific immune response to foreign antigen mainly occur?
-Lymph nodes
most likely sites where specific immune responses develop against bacteria causing a skin infection?
-Lymph nodes
All the following cell types can present antigen to T helper cells, EXCEPT:
-monocyte
-macrophage
-dendritic cell
-neutrophil
-neutrophil
All the following are characteristics of a strong immunogen EXCEPT:
-it is a large molecule
-it is protein in nature
-it is a repeating polymer
-it is foreign to the host
-it is a repeating polymer
A macromolecule that is capable of eliciting an immune response in an immunocompetent individual is called:
-an antigen
Which of the following is characteristic of natural immunity?
-T lymphocytes play a major role
-It involves memory
-it involves specificity
-mechanisms are always present and fully functional
mechanisms are always present and fully functional
Which complement components has chemotactic activity?
C3a
the condition that could result from a deficiency in complement C2.
Immune complex disease
What is cleaved by C3bBb?
C3
Which type of cell has a diameter between 10 and 15 micrometers, has a multi-lobed nucleus, and usually comprises more than 50% of circulating leukocytes?
-Neutrophil
Antibodies are secreted by:
plasma cells
Which of the following is a characteristic of natural killer cells?
-They are a type of lymphocyte
-They are part of the adaptive immune system
-They are smaller than B and T cells
-They mature in the thymus
They are a type of lymphocyte
What is a low-molecular-weight molecule that has one binding site for an antibody?
Hapten
An antigenic determinant is also called:
-an epitope
Hematopoietic stem cells are located in the:
-bone marrow
Which white cell in the peripheral blood migrates into tissue to become a macrophage?
-Monocyte
Which of the following is NOT a component or characteristic of natural (innate) immunity?
-Repeated exposure to a pathogen does not change the response
-The response involves phagocytosis
-The response involves acute-phase reactants
-The response involves antibodies
-The response involves antibodies
A substance that is too small to stimulate antibody production by itself unless it is attached to a larger carrier molecule is called:
a hapten
The anaphylotoxins are produced by proteolytic cleavage of:
C5 and C3
T cells mature in the:
thymus
Contact with antigen and activation of B cells normally occurs in the:
-lymph nodes
Which of the following are components play a role in initiating both innate and adaptive immune responses?
-T helper cells -B cells -Immunoglobulins -Macrophages
-Macrophages
A 50-kDa protein from a bacterial cell that has numerous different epitopes would be called:
-an immunogen and an antigen
Which of the following would be the most effective immunogen?
-One with a molecular weight of less than 10,000 Da
-One that is genetically foreign and has a single epitope
-One with multiple epitopes with a single repeated specificity
-One with multiple epitopes with many specificities
One with multiple epitopes with many specificities
