Lab Exam 2 Flashcards

1
Q

Diseases with homogenous pattern

A

-high titer-SLE
-Low iter other CTD (Connective tissue diseases)

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2
Q

antigens associated with homogenous

A
  • dsDNA
  • ssDNA
  • DNP
  • histone
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3
Q

Diseases with peripheral pattern

A
  • High titer-SLE
  • MCTD (Mixed Connective Tissue Disease)
  • Scleroderma
  • Sjogren’s Syndrome
  • Low titer other CTD (Connective Tissue Disease)
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4
Q

antigens associated with peripheral

A
  • Sm (Smith Antigen) – highly specific for SLE
  • RNP
  • Scl-70
  • SS-B
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5
Q

diseases with speckled

A
  • SLE
  • Mixed Connective Tissue Disease (MCTD)
  • Sjogren’s Syndrome (SS)
  • Scleroderma
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6
Q

antigens associated with speckled

A
  • SS-B
  • Scl-70RNP
  • Sm (SLE)
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7
Q

Diseases associated with nucleolar pattern

A
  • High titer Scleroderma
  • Sjogren’s Syndrome
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8
Q

Antigens associated with nucleolar?

A
  • 4-65 RNA
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9
Q

diseases associated with Anti-centromere AB (ACA)

A

CREST

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10
Q

antigens associated with Anti-centromere AB (ACA)

A

Centromere

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11
Q

Cytoplasmic Staining:

Mitochondrial (AMA) is associated with what diseases?

A
  • Biliary Cirrhosis
  • Other liver diseases
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12
Q

Cytoplasmic Staining:

Mitochondrial (AMA) pattern is associated with what antigen?

A

mitochondira

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13
Q

Cytoplasmic Staining:

smooth muscle pattern is associated with what diseases?

A
  • Mononucleosis
  • Chronic hepatitis
  • Other Liver Diseases
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14
Q

Cytoplasmic Staining:

smooth muscle pattern is associated with what antigen?

A

actin

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