Quinolonas Flashcards

1
Q

Quinolonas

Generaciones

A
  1. Ácido nalidixico
  2. Norfloxacina, ciprofloxacina, levofloxacina
  3. Moxifloxacina
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2
Q

Quinolonas

Mecanismo

A

Inhibición de ADN girasa (-) y topoisomerasa IV (+)

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3
Q

Quinolonas

Uso

A

Infecciones en hueso y articulaciones, pseudomonas : ciprofloxacina

Respiratorias: moxifloxacina

Antrax

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4
Q

Quinolonas

Efectos adversos

A

No en embarazo
Colitis por clostridium

Causa ruptura del tendón de Aquiles

Prolonga QT

Hipoglucemia con levo

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5
Q

Mecanismo

A

Solo en IVU

Inhibe sistemas enzimaticos

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6
Q

Resistencia

A

E. Coli

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7
Q

Absorción

A

VO con alimentos

14 días + descanso

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