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Farma > Antimicoticos > Flashcards

Antimicoticos Flashcards

1
Q

Anfo B

Generalidades

A

Anfoterico

Fungostatico o fungicida

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2
Q

Anfo B

Mecanismo de acción

A

Une ergosterol
Incrementa permeabilidad
Estimula sistema inmune
Radicales libres

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3
Q

Anfo B

Uso

A 
Aspergilosis 
Blastomicosis del SNC
Candidiasis
Cocci 
Criptococos
Histoplasmosis diseminada
Esporotricosis cutanea
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4
Q

Anfo B

Absorción

A

No por GI

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5
Q

Anfo B

Toxicidad

A

Nefrotoxicidad

Disminuye con lípidos, dispersión coloidal

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6
Q

Fluconazol e itraconazol

Generalidades

A

Triazoles

Interfieren en síntesis de ergosterol (14 a esterol desmetilasa )

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7
Q

Fluconazol

Generalidades

A

Absorción GI casi completa excreción renal

En saliva, leche y esputo

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8
Q

Fluconazol

Uso

A

Cándida
Criptococos
Cocci
Paracocci

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9
Q

Fluconazol

Efectos adversos

A

Raros: alopecia, stevens johnson

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10
Q

Itraconazol

Uso

A 
Aspergillus
Blastomicosis 
Cocci
Histoplasmosis
Mucormicosis
Esporotricosis
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11
Q

Itraconazol

Absorción

A

Aumenta 30% con comida

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12
Q

Terbinafina

Mecanismo de acción

A

Inhibe escualeno epoxidasa que bloquea síntesis de ergosterol

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13
Q

Terbinafina

Biodisponibilidad

A

Disminuye por efecto de primer paso

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14
Q

Terbinafina

Efectos

A

Rifa disminuye

Cimetidina aumenta

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15
Q

Miconazol

Uso

A

Candidiasis, tiña

Seguro en embarazo

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16
Q

Nistatina

Generalidades

A

Similar a anfo B

Solo para candidiasis

17
Q

Cotrimazol

Generalidades

A

En vagina

Farma (11 decks)

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