Lepra Flashcards

1
Q

Dapsona

Mecanismo

A

De las sulfonas
Análogo de PABA
Inhibe digidropteroato sintasa (resistencia)
Inhibe microtubulos de leucocitos (limita inflamación)

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2
Q

Dapsona

Generalidades

A

Bacteriostatico contra m. Leprae

Absorción oral completa

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3
Q

Dapsona

Efectos adversos

A

Hemolisis
Metahemoglobinemia
Hipersensibilidad
Neuropatia periferica

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4
Q

Clofazimina

A

Se usa en casos de resistencia o o tolerancia

Causa intolerancia digestiva, pigmentación, fotosensibilidad

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