Questions - Prions Flashcards
1
Q
What is the key difference between disease causing prion proteins and normal cellular prion proteins?
A
The folding because the amino acid sequence is the same
2
Q
What is the most common form of human prion disease?
A
Creutzfeldt-Jakob Disease (CJD)
3
Q
Which prion disease is caused by cannibalism?
A
Kuru
4
Q
Which prion disease is hereditary?
A
Familial CJD (variation of Creutzfeldt-Jakob Disease) GSSS
5
Q
Which prion disease is acquired?
A
Iatrogeinc CJD Variant CJD (mad cow)
6
Q
Does CJD risk increase with age?
A
Yes