Questions - Prions Flashcards

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1
Q

What is the key difference between disease causing prion proteins and normal cellular prion proteins?

A

The folding because the amino acid sequence is the same

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2
Q

What is the most common form of human prion disease?

A

Creutzfeldt-Jakob Disease (CJD)

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3
Q

Which prion disease is caused by cannibalism?

A

Kuru

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4
Q

Which prion disease is hereditary?

A
Familial CJD (variation of Creutzfeldt-Jakob Disease)
GSSS
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5
Q

Which prion disease is acquired?

A
Iatrogeinc CJD
Variant CJD (mad cow)
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6
Q

Does CJD risk increase with age?

A

Yes

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