Questions - Hepatitis Flashcards
Which Hepatitis virus is the only DNA Hep virus?
Hepatitis B
Which Hepatitis virus replicates via an RNA intermediate?
Hepatitis B
Which Hepatitis virus has reverse transcriptase?
Hepatitis B
What is most common cause of acute hepatitis?
HAV
What is most common cause of chronic hepatitis?
HCV
What two viruses does the Hepatitis B vaccine protect against?
Hep B and Hep D
Which Genotype of Hepatitis C is the most common strain in the US?
Genotype 1
Which Hepatitis C drug is not so functional with genotype 1a hep C virus with an NS3 Q80K polymorphism?
Olysio (Simeprevir) [protease inhibitor]
Which Hepatitis C drug is given to patients who cannot tolerate INF (interferon) or are on a liver transplant list (do not have a functional liver)?
Sofosbuvir (Sovaldi)
Ritonavir boosts blood levels of what other Hepatitis C drug?
Paritaprevir
Which Hepatitis C drug is not recommended for patients whose liver is unable to function properly (decompensated cirrhosis)?
Viekira Pak
Which Hepatitis C drug can be used patients whose liver is unable to function properly (decompensated cirrhosis)?
Sofosbuvir and Harvoni (combination pill which includes Sofosbuvir and Ledipasvir)
Which was the 1st drug to demonstrate safety and efficacy in Hepatitis C genotype 3 without needing interferon or ribavirin?
Daklinza (daclatasvir)
Which was the 1st Hepatitis C drug to treat all 6 major forms of HCV?
Epclusa (sofosbuvir + velpatasvir)
Which Hepatitis C medication can treat patients with or without cirrhosis?
Epclusa (sofosbuvir + velpatasvir)
