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Microbiology - Exam 2 > Questions - Genomics > Flashcards

Questions - Genomics Flashcards

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1
Q

All viruses contain either DNA or RNA as the genetic material, what is the exception?

A

Cytomegalovirus, traditionally a double stranded DNA virus but has also RNA strands

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2
Q

All viruses are haploid, what is the exception?

A

retroviruses (diploid)

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3
Q

DNA virus proteins enter the nucleus to replicate, what is the exception?

A

POX Virus

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4
Q

RNA viruses proteins remain in the cytoplasm to replicate, what is the exception?

A

Retroviruses

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5
Q

What is the genetic mechanism that could create an antigenic shift in influenza virus?

A

Reassortment (a mixing and matching of segments)

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6
Q

Do RNA viruses accumulate more mutations than DNA viruses?

A

Yes. Why? No proofreading

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7
Q

In replication there are 2 kinds of RNA polymerases: RNA dependent RNA polymerase and RNA dependent DNA Polymerase. What is another name for RNA dependent DNA polymerase?

A

Reverse transcriptase.

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8
Q

Which type of virus hits the ground running?

A

Plus stranded RNA

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9
Q

Which is the only DNA virus that has single stranded DNA?

A

Parvovirus B19

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10
Q

What genomic material do herpes viruses have?

A

Double stranded DNA

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11
Q

Exception to the rule of plus single stranded RNA virus is going to be directly made into mRNA?

A

HIV. There are two copies of the plus single stranded RNA (Diploid)

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12
Q

Segmented genomes can engage in what type of genetic interaction?

A

Reassortment

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13
Q

What genetic mechanisms can segmented viruses engage in that gives them a big jump in genetic composition?

A

Reassortment

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14
Q

Which influenza virus shows antigenic shift (major genetic composition changes)?

A

Influenza A (because it affects many animal species)

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15
Q

What is another name for recombination?

A

Copy choice

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16
Q

Which types of viruses does recombination take place in?

A

RNA viruses only

17
Q

What are the 6 steps in the life cycle of an animal virus?

A 
Adsorption
Penetration
Uncoating
Synthesis
Assembly
Release from the host cell
18
Q

What is tropism?

A

The affinity of a virus for a particular cell type (i.e. tropism for hepatocytes)

19
Q

Which is the smallest human DNA virus?

A

Parvovirus B-19

20
Q

Which is the only single stranded Arbovirus?

A

La Crosse Encephalitis (also only segmented one)

21
Q

Which virus shows antigenic shift (reassortment) and antigenic drift (regular, seasonal epidemics)?

A

Influenza Virus (shift only in Influenza A)

22
Q

Which viruses have a segmented genome?

A

LA-LA CO INFected HANa and ROTA

La Crosse
Lassa Fever
Coltivirus
Influenza
Hantavirus
Rotavirus

Microbiology - Exam 2 (16 decks)

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