Questions - Immunization Flashcards
Serological methods give a definitive diagnosis of which virus is causing the infection, which virus is the exception?
Flaviviridae family (Zika, Japanese encephalitis, Dengue, West Nile Encephalitis) which has a cross reaction between members of the family so the Serological method is not conclusive.
Which 2 killed whole cell vaccines have serum immunoglobulins (immediate protection)?
Rabies
Hep A
also IPV
Is serum immunoglobulin long term or short term protection?
Short term because it does not actively engage the person’s immune system.
If Varizig is being given to an immunocompromised person, what type of immunization is this?
Passive, artificial
Which is the only virus where a vaccine is given to a pregnant infected woman even though it puts her child at risk?
Smallpox
Which virus has a recombinant vaccine?
Hepatitis B
What is the post exposure prophylaxis regimen for measles?
Shot of measles vaccine within 72 hours of exposure
or shot of serum immunoglobulins within 6 days of exposure
Why is MMR vaccine so successful in preventing measles?
Measles is limited to humans and immunity is lifelong. Also, only one serotype of measles.
Which viruses have serum immunoglobulins for post exposure prophylaxis?
- Hep A and B
- Measles
- Rabies
- Chickenpox and Shingles
- CMV
- Parvovirus B19
Which viruses have inactivated fractional subunit vaccines?
Japanese Encephalitis
Hep B
Influenza
What is the post exposure prophylaxis for Varicela Zoster (Chickenpox, Shingles)?
Varizig within 5 days for immunocompromised people
What is the post exposure prophylaxis for smallpox?
Vaccine 3-6 days after exposure
