PVD Clin Med Final Flashcards
PAD (arterial)
underdiagnosed, undertreated, highly preventable
PAD
powerful, independent predictor of mortality
Atherosclerosis
Hardening
development of fatty streaks (thickened intima and accumulation of foam cells)
plaque and such
Vulnerable plaque- burst and trigger a blood clot
Atherosclerosis
frequently occurs at bifurcations: aortic, iliac, femoral
Atherosclerosis affects:
more than 85 of adults >50 YO
Contributors of Atherosclerosis
Endothelial dysfunction, Inflammatory factors, Immunologic factors, Plaque ruptures, Age
Endothelial dysfunction
HTN, DM, Hypercholesterol, Smoking
Acute limb ischemia
Potential threat to limb viability
Chronic limb ischemia
meaning pt came in later than 2 weeks after onset of acute event
Groups at risk for PAD
70 or older 50-69 w hx smoking or DM 40-49 w DM and at least one other risk factor Leg sx: claudication or pain at rest Known atherosclerotic at other site
PAD risk factors
HTN, DM, Dyslipidemia, Smoking, Age, obesity >30BMI, fam hx
Claudication
intermittent discomfort in a certain muscle group, worse with exercise and relieved with rest
Leriche syndrome
Claudication
Absent/diminished femoral pulse
Erectile dysfx
Aortoiliac disease
buttock and hip claudication
Aortoiliac or common femoral artery disease
thich claudication
Superficial femoral artery stenosis
upper 2/3 calf claudication
Popliteal artery stenosis
lower 1/2 calf claudication
Tibial or Peroneal artery stenosis
foot claudication
Insufficient flow AT REST
Threatened limb!
10% pts w PAD
Ischemic rest pain
pain in forefoot/toes WORSE W ELEVATION
Critical limb ischemia
rest pain
non healing wound/ulcer
Skin discolor/gangrene
pain when elevated, redness when lowered
PAD physical findings
blue, pale with elevation, dependent redness, thin, dry, shiny, and hairless
PAD physical findings
brittle nails, cool temp, delayed cap refill, diminished pulse
ABI
Ankle-brachial index
Ankle systolic/brachial systolic
ABI 0.90 or less with exertional sx is diagnostic for PAD
Arterial Duplex Doppler US
determine velocity of blood flow
can show site and severity of % stenosis
Contrast arteriography (angiogram)
GOLD STANDARD for definitive dx for PAD
Advanced imaging for PAD
CTA and MRA (takes longer, used to plan revascularization procedures)
PAD management
ASA or PLAVIX stop smoking Lipid lowering (Statin) Control sugar and BP weight loss/diet
Tx for claudication sx
supervised exercise
Cilostazol - phosphodiesterase inhibitor
PAD: revascularization
Endovascular (first line)
used for CRITICAL limb ischemia (pain at rest, ulcer, gangrene)
Endovascular procedure options
Angioplasty
Stent
Atherectomy
Surgical options
Bypass graft
Acute arterial occlusion
leads to limb ischemia
usually d/t thromboembolism
Atheroembolism
cholesterol embolism
6 P’s of Acute Arterial Occlusion
Paresthesia Pain Pallor Pulselessness Poikilothermia-coolness Paralysis
Management of Acute arterial occlusion
Emergency surgical consult
Anticoag: Heparin Thrombolytic Thrombectomy surgical bypass Amputation
Chronic Venous Disease
Telangiectasis 50-60%
Varicose veins 10-30%
Chronic venous infuff 1-5%