Clin Med Flashcards
Exam 1
Griseofulvin 6-12 weeks, systemic antifungal
Tinea Capitis
Kerion & Favus appear in more severe cases
Tinea Capitis
Associated sx: Cervical adenopathy, dermatophytid rxn, erythema nodosum (rare)
Tinea capitis
Caregivers of child affected by tinea capitis, athletes w skin to skin, immunocomp
Tinea Corporis “ringworm”
Itchy, annular, erythematous plaque
Tinea Corporis “ringworm”
raised advancing border
Tinea Corporis “ringworm”
DO NOT USE STEROID, can atrophy skin & alter appearance of rash
Tinea Corporis “ringworm”
Tinea Cruris “jock itch”
well marginated, scaly, annular plaque w/ raised border
Scrotum spared, pruritis & pain, starts @ inguinal fold & extend to inner thigh
Tinea Crurus “jock itch”
Most common dermatophytosis in the world
Tinea Pedis
Itchy, painful vesicles/bula following sweating
Tinea Pedis
Secondary staph infection is common d/t scratching & de-roofing vesicle
Tinea Pedis
“Moccasin Ringworm” sharp demarcation & accumulation of scales in skin crease is a chronic version of what
Tinea Pedis
“Tinea Manuum”
version of Tinea Pedis: 2 feet & 1 hand (the scratcher hand)
Tx of Tinea Pedis
LONGER. Clotrimazole for 4 weeks & Wet Burow’s dressing
Onychomycosis
Tx depends on type
Dermato: Oral Terbinafine
NonDermato: Itraconazole
Tx of Onychomycosis
fingernails 6 wks
toenails 12 wks
Most common type of onychomycosis
Distal subungual
Candidal Intertrigo
skin fold disease!
Candidal Intertrigo
Tx: Nystatin (topical) &
Fluconazole (systemic)
Erythematous, macerated (soggy) plaques and erosions in skin folds
Satellite pustules/papules
Fine, peripheral scaling
Candidal Intertrigo
Tinea Versicolor AKA Pityriasis Versicolor
Etio: Malassezia Furfur. Normal skin flora –> mycelial form
Tinea Versicolor tx:
Topical Antifungal: CLotrimazole, Selenium sulfide shampoo/lotion/foam, Zinc pyrithione shampoo OR
Systemic Itraconazole
Tinea Versicolor
tropical climate, teens/ young adults. NOT CONTAGIOUS
Macules/patches on trunk & arms, can coalesce, often have fine scale. Asymptomatic other than mildly pruritic
Tinea Versicolor
Burrow is pathognomic
Scabies
insect w/ 30 day lifespan. Eggs hatch in 10 days
Scabies
Tx of Scabies
Permethrin Cream 5% (again 10-14 days later) & Oral Ivermectin (again 14 days later)
Pubic Lice
Permethrin 1% cream
Acne Vulgaris
4 main factors: follicular hyperkeratinization, increased sebum production, cutibactreium acnes w/in follicle, inflammation
Rapid appearance of this w/virilization suggests underlying problem- work up for adrenal or ovarian tumer or hyperandrogenism
Acne Vulgaris (be cautious with rapid appearance)
Comedonal (non inflammatory) acne vulgaris
Topical Retinoid (Tretinoin cream)
Mild PP & mixed acne
Topical Retinoid, Benzoyl Peroxide, +/- Topical Abx (Erythromycin, Clindamycin)
Moderate PP & mixed acne
Topical Retinoid, Benzoyl Peroxide, and Oral Abx (Tetracycline)
Severe acne
Topical Retinoid, Benzoyl Peroxide, and Oral Abx OR Oral Isotretinoin Monotherapy
Tx for Acne Vulgaris in Pregnancy
Topical Clindamycin, Topical Azelaic acid, Oral Erythromycin (DO NOT use peroxide)
Erythematotelangiectactic Rosacea
telangiectasis.
1st line tx: behavior mod
2nd line tx: Laser light therapy, Topical Brimonidine
Papulopustular Rosacea
NO COMEDONES
Papulopustular Rosacea
1st and 2nd line: Topical
Mod-severe: Tetracyclines (doxy, mino, tetra) & Macrolides (___mycin)
Phymatous Rosacea (hypertrophy)
Tx: Early: Isotretinoin
Advanced: Surgical debulking, laser ablation
Ocular Rosacea
dry eyes, pain, itchy, blurry vision, sensitive, blepharitis, conjunctivitis, stye
tx for Ocular Rosacea
Topical abs & Cyclosporin, Oral Abx REFER OUT
venom includes neurotoxin causing hyperexcitability and excessive neuromuscular activity
scorpion sting
tx for Scorpion sting
symptomatic, Tetanus, observation
Do not give ____ with Antivenom
Benzos!
Local rxn bee sting
swelling & erythema for hours-2 days
tx: cold compress
Large local rxn- bee sting
exag erythema & swelling, getting bigger over time. lasts 5-10 days
tx: cold compress, Prednisone, Antihistamine, NSAID
Secondary bacterial inf d/t bee sting
worsenign over 3-5 days, fever
tx: abx
Anaphylaxis
IM Epinephrine
Widow Spider Bite- if no venom is injected
blanched circular patch with surrounding red perimer, central punctum
Widow Spider Bite- if venom is actually injected
Catecholamine release- intmt radiating pain, abd pain, CP, back pain, muscle spasm, local/regional sweating, hA, N/V
tx: sx, Tetanus, Muscle relaxer, Antivenom if severe
Recluse Spider BIte
Necrotic Bite! in severe cases
Recluse spider
6 eyes
Recluse spider bite- minor case
painless at first –> increase over 2-8 hrs
red plaque or papule w/ central pallow (may see bite marks)
vesiculation can occcur
Recluse Spider Bite- NECROTIC severe
dark depressed center after 1-2 days w/ chills, HA, fever and rarely- renal failure, anemia, hypotension, DIC, Rhabdomyolosis
Vitiligo
autoimmune against melanocytes. mild, white macules with homogenous depigmentation. well defined borders
Tx for Vitiligo
Topical & systemic corticosteroids Calcineurin inhibitor UV phototherapy Skin graft Sunscreen, make up, screen for stress
Hidradenitis Suppurativa “Acne Inversa”
chronic inflammatory condition involving the hair follicle
common places: Axillary, Inguinal, Anogenital
F>M
Hidradenitis Suppurativa “Acne Inversa”
starts w/ single deep seated inflammatory nodule
Follicular occlusion –> rupture –> immune response
Hidradenitis Supp “Acne Inversa”
Purulent drainage, sinus tract, comedones, scarring
Tx for “Acne Inversa”
Local: Clinda & Intralesional Corticosteroid
Anti-androgenic agents
Systemic: Doxy or Mino
Surgery: Punch Deb or Wide Exc
Severe: TNH inhibitor & Oral Retinoid
Atopic Eczema
chronic, non contagious, inflammatory skin disease
FLG gene mutation, Type I hypersensitivity IgE mediated
Atopic Eczema
ill defined, erythematous, scaling patches –> edematous papules & vesicles
Complication assoc w/ Atopic Eczema
Eczema Herpeticum- viral infection of HSV 1
Tx of Atopic Eczema
Topical/Oral steroids
Calc Inhibitors (Pimecrolimus Elidel cream & Tacrolimus Protopic ointment)
+/- Antihistamine
Gold standard: Petroleum vaseline
Lichen Simplex Chronicus
AKA Neurodermatitis
Neurodermatitis/ Lichen Simplex Chronicus
caused by excessive itching. Leathery appearance, pigmentation, exagg skin marking
tx: STOP itching, high potency topical steroid, moist, antidepressant, antihistamine
Dyshidrotic Eczema/ Dyshydrosis/ Pompholyx
Tapioca, VERY ITCHY, vesicles coalesce & rupture
Dyshidrotic Eczema
worse with stress and hot weather
tx: Reassurance, Burow’s dressing (Domebror solution) topical steroids