pulmpath2

Question 1

What do obstructive diseases limit?

Answer 1

limitation of airflow
increase in resistance due to partial or complete obstruction
-have trouble letting the air out

Question 2

What does a restrictive disease reduce?

Answer 2

reduces expansion of lung parenchyma

Question 3

What are examples of obstructive airway diseases, how is the FEV1 affected?

Answer 3

Decreased FEV1
-increase in resistance to airflow due to obstruction at any level

EX:

1. emphysema
2. chronic bronchitis
3. bronchiectasis
4. asthma
5. tumor
6. foreign body

Question 4

What are examples of obstructive airway diseases, how is the FEV1 and TLC affected?

Answer 4

Normal FEV1, Decreased TLC
-reduced expansion of lung parenchyma with decrease in total lung capacity

EX:
Chest wall disorders (polio, obesity, pleural disease, kyphoscoliosis)
Interstitial/ Infiltrative diseases (ARDS, dust disease, interstitial fibrosis)

Question 5

What does a pulmonary function curve look like in obstructive vs. restrictive lung disease?

Answer 5

Obstructive-shift in curve but size remains the same

Restrictive-same shape but smaller

Question 6

What are 4 key obstructive pulmonary diseases?

Answer 6

1. Asthma
2. chronic bronchitis
3. emphysema
4. bronchiectasis

Question 7

What is asthma?

Answer 7

intermittent and reversible airway obstruction

• increased responsiveness of the tracheobronchial tree to various stimuli
• multiple genes+environment
• chronic bronchial inflammation with eosinophils
• bronchial smooth muscle hypertrophy hyperreactivity
• increased mucus production