Anxiety Flashcards
Fear vs Anxiety
Fear: emotional response to real or perceived threat
Anxiety: anticipation of future threat
anxiety disorders often have both
What causes anxiety to become pathological?
- Autonomy
- Intensity
- Duration
- Behavior-dysfunctional behaviors
Amygdala centered circuit:
fear, panic, phobia
Cortico-striatal-thalamic-cortical
worry, anxious misery, apprehension, expectation, obsessions
What are the neurotransmitters that are indicated in anxiety?
- Serotonin-raphe nuclei-low=aggression, impulsivity, depression, suicide attempts, self-injury, intrusive thoughts and repetitive behavior
- Ne-Locus ceruleus
associated with orienting, selective attention, hypervigilance, mood and autonomic arousal - GABA-increase gaba-alleviate anxiety
- glutamate-learning and memory
Male vs female anxiety
female
Panic Attack
abrupt surge of intense fear that reaches a peak within 10 minutes and 4 or more occur Palpitations Paresthesias Abdominal Distress Nausea Intense fear of dying I-lIghtheadedness Chest pain Chills Chocking C disConnectedness Sweating Shaking SOB
4 or more four panic attack within 10 minutes
Panic Disorder
unexpected panic attacks with no identifiable trigger. at least one attack is followed for 1 month by anticipatory anxiety
- worry about an additional attack or the consequences of an attack
- significant maladaptive change in behavior related to the attack
Can panic attacks occur in any generalized anxiety disorder?
yes
What is the most common anxiety disorder comorbidity ?
agoraphobia: avoid places or situations that might cause you to panic and make you feel trapped, helpless or embarrassed
2nd most common: GAD
What is the most common non-anxiety comorbidity to anxiety?
major depression
Others:
alcohol>other substances
personality disorders-especially cluster C
What is the median age of onset of an anxiety disorder?
20-24
What are the symptoms of anxiety?
Physical symptoms:..
Affective: edginess to terror and panic; often viewed as irritability or restlessness
Cognitive: worry apprehension, poor concentration, mind blank, tense/jumpy, anticipate the worst
Behavioral: made an effort to diminish or avoid the stress; response can be checking behaviors, rituals, avoidance
–Without treatment: WAXING AND WANING
When are panic attacks and disorders risk factors for suicide?
diagnosis in the prior 12 months
What is the neurocircuitry model theory of anxiety?
abnormally sensitive fear network, centered in amygdala
GABA, serotonin, norepinephrine, implicated