Pulmonary Medications Flashcards

1
Q

What is the primary function of the respiratory system?

A

Mediates gas exchange between the environment and bloodstream.

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2
Q

What are the main components of the upper respiratory tract?

A

Moves air to the lower respiratory tract, removes debris and pollutants, humidifies and conditions the air.

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3
Q

What occurs in the alveoli of the lower respiratory tract?

A

Gas exchange between the air and the blood occurs.

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4
Q

What are the main goals of pulmonary medications?

A

Bronchodilation, facilitation of mucociliary clearance, increased alveolar ventilation, improved control of breathing pattern.

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5
Q

What are bronchodilators used for?

A

To maintain airflow, manage infections, and manage allergies.

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6
Q

Name two long-acting beta-adrenergic agonists (LABAs).

A

Salmeterol (Serevent), Formoterol (Foradil).

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7
Q

How are short-acting beta-adrenergic agonists (SABAs) commonly delivered?

A

Orally, subcutaneously, or via inhalation (preferred method).

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8
Q

What is a metered dose inhaler (MDI)?

A

A portable device that delivers a specific amount of medication to the lungs in the form of a short burst of aerosolized medicine.

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9
Q

What is a nebulizer and how does it work?

A

A device that delivers medication in the form of a mist inhaled into the lungs, commonly used in hospital settings.

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10
Q

What are the main benefits of using a short-acting beta-adrenergic agonist (SABA)?

A

Quick relief of symptoms, considered for rescue therapy, prevents/decreases bronchospasms.

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11
Q

Name a common SABA.

A

Albuterol (ProAir).

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12
Q

What are the primary uses of long-acting beta-adrenergic agonists (LABAs)?

A

Maintenance drugs to provide stable airways, help with symptoms of COPD, improve sleep, reduce the need for reliever medications.

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13
Q

Name a common LABA.

A

Salmeterol (Serevent).

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14
Q

What do parasympatholytic agents or muscarinic antagonists do?

A

They improve bronchodilation by blocking muscarinic receptors that cause bronchoconstriction.

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15
Q

Name two common parasympatholytic agents.

A

Ipratropium (Atrovent), Tiotropium (Spiriva).

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16
Q

What is the function of methylxanthines?

A

Block enzyme action to improve bronchodilation, stimulate CNS and skeletal muscle to improve diaphragmatic contractility and reduce fatigue.

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17
Q

Name a common methylxanthine.

A

Roflumilast (Daliresp).

18
Q

What are corticosteroids used for in pulmonary medicine?

A

Reduce the inflammatory response that causes bronchoconstriction.

19
Q

What are mast cell stabilizers used for?

A

Prevent release of histamine and other inflammatory mediators, reduce inflammatory response.

20
Q

Name a common mast cell stabilizer.

A

Cromolyn (Intal).

21
Q

What are leukotriene inhibitors used for?

A

Inhibit leukotrienes that promote bronchoconstriction and inflammation.

22
Q

Name a common leukotriene inhibitor.

A

Montelukast (Singulair).

23
Q

What are decongestants used for?

A

To relieve runny nose, mucosal swelling, and fluid lead from colds or respiratory infections by causing vasoconstriction.

24
Q

Name two common decongestants.

A

Ephedrine, Pseudoephedrine (Sudafed).

25
Q

What are antihistamines used for?

A

To treat seasonal allergies and respiratory allergic responses by decreasing mucosal congestion, irritation, and discharge.

26
Q

Name three common antihistamines.

A

Diphenhydramine (Benadryl), Loratadine (Claritin), Cetirizine (Zyrtec).

27
Q

What are antitussives used for?

A

To manage cough associated with respiratory symptoms, suppress ineffective dry hacking cough.

28
Q

Name two common antitussives.

A

Benzonatate (Tessalon), Codeine.

29
Q

What are mucolytics used for?

A

Decrease thickness of mucus by disrupting the bonds of mucoid and purulent secretions.

30
Q

Name a common mucolytic.

A

Acetylcysteine (Mucomyst).

31
Q

What are expectorants used for?

A

Facilitate expectoration of respiratory secretions by increasing hydration of airway or volume of secretions.

32
Q

Name a common expectorant.

A

Guaifenesin (Mucinex).

33
Q

What are respiratory stimulants used for?

A

Stimulate the central respiratory center to increase ventilation.

34
Q

Name a common respiratory stimulant.

A

Doxapram (Dopram).

35
Q

What are respiratory depressants used for?

A

To manage anxious breathing and agitation by suppressing ventilatory drive.

36
Q

Name two common respiratory depressants.

A

Sedatives, Narcotics.

37
Q

What are the main considerations for pulmonary rehabilitation?

A

Focus on respiratory hygiene, increase effectiveness of medications, postural drainage, breathing exercises, monitor vital signs.

38
Q

How can bronchodilators improve respiratory function?

A

By improving airway diameter and reducing resistance, thus enhancing airflow and oxygenation.

39
Q

What should be monitored during pulmonary rehabilitation?

A

Monitor vital signs, including heart rate and EKG, for any abnormalities.

40
Q

What should be done if non-cardiac symptoms such as nervousness or tremors are observed during pulmonary rehabilitation?

A

Notify the physician due to potential toxicity risk.

41
Q

What should be done to reduce the risk of oral infection after using an inhaler?

A

Gargle with mouthwash or water to reduce risk of oral infection, throat irritation, or hoarseness.