Pulmonary HTN & Cor Pulmonale Flashcards

1
Q

Define pulm HTN (PAH)

A
  • increased pulm a. pressure –> RV hypertrophy –> R side heart failure
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2
Q

What does the right ventricle best respond to?

A
  • volume changes/expansion
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3
Q

Define Group 1 PAH

A
  • increased pulm a. pressure with normal capillary wedge pressure
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4
Q

Define Group 2 PAH

A
  • increased pulm a. pressure & pulm capillary wedge pressure
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5
Q

What is also seen in Group 2 PAH?

A
  • left sided atrial or ventricular heart disease

- left sided valvular disease

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6
Q

Define Group 3 PAH?

A
  • chronic hypoxia with mild increase of pulm a. pressure
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7
Q

Define Group 4 PAH?

A
  • elevated pulm a. pressure with documented pulm a. obstruction for > 3mo
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8
Q

Define Group 5 PAH?

A
  • elevated pulm a. pressure in association with systemic disease & unclear mechanism
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9
Q

What are the symptoms of PAH?

A
  • dyspnea w/ exertion
  • chest pain
  • fatigue
  • lethargy
  • weakness
  • syncope
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10
Q

What labs should be drawn for PAH and what does it show?

A
  • CBC: polycythemia 2ndary to chronic hypoxia
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11
Q

What diagnostic studies should be ordered for PAH?

A
  • CXR
  • EKG
  • Echo
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12
Q

What will a CXR show in PAH?

A
  • enlarged pulmonary a.
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13
Q

What will an EKG show in PAH?

A
  • RVH
  • right atrial hypertrophy
  • RV strain
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14
Q

What will an Echo show in PAH?

A
  • ejection fraction
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15
Q

What is the 1 definitive diagnostic test for PAH?

A
  • right heart cath
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16
Q

What is the treatment for Group 1 PAH?

A
  • Ca+2 channel blockers
  • endothelial receptor antagonists
  • phosphodiesterase-5 inhibitors
  • prostacyclines
  • lung transplant
17
Q

What is included in the group of prostacyclines used to treat Group 1 PAH?

A
  • iloprost
  • epopprostenol
  • preprostinil
18
Q

What is the treatment for Group 2-5 PAH?

A
  • tx underlying dz
19
Q

What is the f/u for PAH?

A
  • q 3mo w/ labs prior to appt
20
Q

Define cor pulmonale

A
  • alteration in the structure & function of the RV caused by a primary disorder of the pulmonary system
21
Q

What causes cor pulmonale?

A
  • MC: PAH
22
Q

What are the symptoms of chronic cor pulmonale related to?

A
  • underlying dz
23
Q

What are the S&S of cor pulmonale?

A
  • dyspnea
  • chronic productive cough
  • wheezing
  • fatigue/weakness
  • orthopnea & PND
  • LE edema
24
Q

What is seen on PE in cor pulmonale?

A
  • increased JVP
  • V wave in JVP
  • tachypnea
  • RV palpable heave
  • decreased ejection fraction
  • hepatomegaly
  • LE edema
  • cyanosis & clubbing
25
Q

What is the gold standard for diagnosing cor pulmonale?

A
  • right heart cath
26
Q

What are the other diagnostic tests for cor pulmonale?

A
  • echo intitial test
  • CXR
  • PFTs
  • spirometry & lung volumes
  • ABG
  • CT
  • V/Q scan
27
Q

What will be drawn for labs and what will be seen in cor pulmonale?

A
  • CBC: polycythemia d/t hypoxia

- SaO2 less than or equal to 85%

28
Q

What will be seen on PFTs in cor pulmonale?

A
  • frequently abnormal
  • MC: impaired diffusion capacity
  • restrictive ventilatory defect
29
Q

What is the treatment for cor pulmonale?

A
  • tx underlying dz

- improve O2 & RV function by increasing RV contractility & decreasing pulmonary vasoconstriction

30
Q

How is cor pulmonale managed?

A
  • salt restriction
  • smoking cessation
  • vasodilators
  • pt educations
31
Q

What are complications of cor pulmonale?

A
  • syncope
  • hypoxia
  • pedal edema
  • passive hepatic congestion
  • death