Lung Cancer Flashcards
_____ ______ is etiologic in ~85% of cases
- cigarette smoking
What is lung CA risk related to?
- pack years
What is the best treatment for lung CA?
- prevention
Nicotine produces _______, stopping produces ______.
- tolerance
- withdrawal
T/F: The majority of patients dx’d w/ lung CA, die of their disease.
- True
What are the most frequent presenting symptoms of lung CA?
- cough
- wt loss
- dyspnea
- chest pain
- hemoptysis
What will be found on physical exam in lung CA?
- asymmetric breath sounds
- basilar dullness
- lymphadenopathy
- organomegaly
- bone tenderness
- unexplained neuro sx
What lab tests should be ordered in lung CA?
- CBC
- chem profile
- PT & APTT
What images should be ordered in lung CA?
- CXR
- chest w/ or w/o abdomen CT
- brain MRI as indicated by S&S
T/F: Treatment should be started before biopsy.
- False!
- no meat, no treat
What are the two categories of epithelial lung CA?
- small cell (SCLCa)
- non small cell (NSCLCa)
Define limited stage lung CA
- limited to 1 side of the chest
Define extensive stage lung CA
- beyond 1 side of the chest
Define Stage 1A lung CA
- ≤ 3cm, N0
Define Stage 1B lung CA
- > 3cm ≤ 5cm, N0
Define Stage 2A lung CA
- ≤ 5cm, N1
- < 5cm ≤ 7cm, N0
Define Stage 2B lung CA
- > 5cm ≤ 7cm, N1
- proximal tumor
- invades thorax, N0
Define Stage 3A lung CA
- mediastinal LNs (+)
Define Stage 3B lung CA
- non-resecatble
Define Stage 4 lung CA
- metastatic
What is the tx for Stage 1A lung CA?
- surgery alone
What is the tx for Stage 1B lung CA?
- surgery +/- chemo
What is the tx for Stage 2A&B lung CA?
- surgery +/- chemo
What is the tx for Stage 3, T3N1 lung CA?
- surgery +/- chemo
What is the tx for Stage 3, N2 or N3, and 3A lung CA?
- combo chemo & radiation
What is the tx for Stage 3B or 4 lung CA?
- palliative chemo
- symptomatic radiation
What is the tx for limited Stage lung CA?
- combo chemo & radiation
What is the tx for extensive Stage lung CA?
- palliative chemo
- symptomatic radiation
What other condition is not uncommon in patients with bone metastases or paraneoplastic syndrome?
- hypercalcemia
What other disease is occasionally associated with SCLCa?
- Cushing’s Syndrome
- Lambert-Eaton Syndrome
What other condition is not uncommon in SCLCa or NSCLCa?
- SIADH (syndrome of inappropriate ADH secretion)
What is common in SCLCa and adenoCA of lung?
- brain metastases
What is a disease almost exclusively a result of asbestos exposure?
- mesothelioma
What is the mainstay of curative tx for NSCLCa?
- surgery
What is the only tx for SCLCa?
- chemo +/- radiation
What is a NCOG Performance Status of 0?
- no disability
- normal ADLs
What is a NCOG Performance Status of 1?
- minor disability
- light work
- no strenuous work
What is a NCOG Performance Status of 2?
- moderate disability
- no work
- can care for self
- in bed some part of waking day
What is a NCOG Performance Status of 3?
- in bed most of day
- some self care
What is a NCOG Performance Status of 4?
- in bed all the time
- no self care
