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Y3 Respiratory Conditions > Pulmonary fibrosis > Flashcards

Pulmonary fibrosis Flashcards

1
Q

Repetitive inflammation in pulm fibrosis leads to

A

Scarring

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2
Q

What worsens that cough in p fibrosis

A

Exertion

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3
Q

Cough dry or productive in p fibrosis

A

Dry

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4
Q

2 Cs signs that are found in fibrosis

A
  • clubbing

- cyanosis

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5
Q

Zone of lung commonly affected by idiopathic p fibrosis

A

Lower

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6
Q

Zone of lung commonly affected by TB related fibrosis

A

Upper

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7
Q

Deficiency of what enzyme can lead to fibrosis

A

Alpha 1 antitrypsine

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8
Q

Connective tissue disorders that can lead to fibrosis

A
  • SLE
  • RA
  • sclerosis
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9
Q

Classic irritants that lead to fibrosis

A
  • asbestos

- coal

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10
Q

Type 3 hypersensitivity condition that leads to fibrosis

A

Hypersensitivity pneumonitis

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11
Q

Triggers of HP

A
  • mould

- bird droppings

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12
Q

Classic professions of HP patients

A
  • bird fanciers
  • farmers
  • mushroom workers
  • malt workers
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13
Q

Why is diagnosing cryptogenic organising pneumonia often delayed

A

Due to presentations similar to pneumonia

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14
Q

What does bronchoalveolar lavarge show in HP

A

++lymphocytes

Mast cells

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15
Q

Asbestiosis commonest risks

A
  • lung fibrosis
  • pleural thickening
  • adenocarcinoma
  • mesothelioma
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16
Q

Drugs that can lead to fibrosis

A
  • nitrofurantoin
  • aminodarone
  • methotrexate
  • cyclophosphamide
  • cabergoline
17
Q

Classic appearance of fibrosis on CXR

A
  • honey comb
  • ground glass
  • thickened walls
18
Q

Auscultation findings in fibrosis

A
  • fine bi-basal inspiratory crackles
19
Q

FEV1/FVC (spirometry) finding in restrictive lung disease

A

<0.7

20
Q

Type of RF found in fibrosis

A

T2RF

21
Q

CRP levels in fibrosis

A

raised

22
Q

Anti-inflam (Sx) given in fibrosis

A

Prednisone

23
Q

TKI given in fibrosis

A

Nintedanid

24
Q

T1RF gas levels & examples

A
  • Hypoxia

- pneumonia

25
Q

T2RF gas levels & examples

A
  • hypoxia & hypercapnia

- asthma; COPD

Y3 Respiratory Conditions (9 decks)

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