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Y3 Respiratory Conditions > Extrapulmonary manifestations of lobar carcinoma > Flashcards

Extrapulmonary manifestations of lobar carcinoma Flashcards

1
Q

Presentation of recurrent laryngeal palsy

A

Hoarse voice

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2
Q

Presentation of phrenic nerve palsy

A

SOB

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3
Q

Which muscle is weakened in phrenic nerve palsy

A

Diaphragm

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4
Q

Presentations of SVC obstruction

A
  • facial swelling
  • difficulty breathing
  • dissented veins in neck & upper chest
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5
Q

Pemberton’s sign (emergency)

A

Raising hands over head —> facial congestion & cyanosis

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6
Q

Sings of Horner’s

A
  • potsis
  • amhidrosis
  • miosis
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7
Q

What structures are pressed by tumour in the following conditions

  • recurrent laryngeal nerve palsy
  • phrenic nerve palsy
  • SVC obstruction
  • Horner’s
A
  • RL nerve
  • P nerve
  • SVC
  • sympathetic glaglion
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8
Q

Presentation of SIADH

A

Hyponatraemia

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9
Q

Cancer type that releases ectopic ADH in SIADH

A

Small cell lung cancer

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10
Q

Cancer type that releases ectopic ACTH in Cushing’s syndrome

A

Small cell lung cancer

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11
Q

Cancer type that releases PTH in hypercalcaemia

A

SCC

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12
Q

Symptoms of limbic encephalitis

A
  • short-term memory impairment
  • hallucinations
  • confusion
  • seizures
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13
Q

Offending tumour in limbic encephalitis

A

Small cell lung cancer

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14
Q

Underlying pathology in limbic encephalitis

A

Immune response against tumour caused by cancer —> inflammation

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15
Q

Antibodies produced in limbic encephalitis

A

Anti-Hu antibodies

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16
Q

Manifestations if muscle weakness (esp proximal & intraocular) in LEMS

A
  • diplopia
  • ptosis (levator muscles)
  • slurred speech & dysphagia ( pharyngeal muscles)
17
Q

Manifestations of autonomic dysfunction in LEMS

A
  • dry mouth
  • impotence
  • dizziness
18
Q

A LEMS manifestation best described as synaptic plasticity and characterised by reduced tendon reflexes

A

Post-tetanic potentiation

19
Q

Tendon reflexes in PTP following a strong muscle contraction

A

Temporarily normal

20
Q

Offending tumour in LEMS

A

Small cell lung cancer

21
Q

Channels targeted by Abs in LEMS (& their location)

A

Voltage-gated Ca channels on presynaptic terminals

Y3 Respiratory Conditions (9 decks)

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