pulmonary embryo & histo Flashcards
what is this a 3D picture of
alveoli
what phase is this
pseudoglandular
what phase is this
canalicular
what phase is this
terminal sac (saccular)
what phase is this
alveolar
function of ciliated epithelium in trachea
mucociliary elevator- washes debris upward
function of cartilage in trachea
holds airway open
function of lamina propria in trachea
holds host defense cells
function of trachealis m. on dorsal surface of trachea
allows esophagus to expand into trachea when swallowing
what cells in lamina propria of trachea perform secretion, & secrete what
goblet cells
secrete mucins
bronchi
-patency due to _____
-epithelium type
-secretory cells
-patency due to cartilage
-pseudostratified
-mucous
alveoli
-patency due to _____
-epithelium type
-secretory cells
-patency due to elastic tissue of lung
-simple squamous
-club cells, type II
first part of airway that no longer has cartilage
bronchioles
type I pneumocytes in alveoli are what tissue type, & function
simple squamous epithelium
gas exchange
type II pneumocytes in alveoli are what tissue type, & function
simple cuboidal epithelium
secretes surfactant
what is the minimum barrier for diffusion of CO2 & O2
2 simple squamous cells & water
function of surfactant
reduces surface tension of water coating alveoli
= keeps alveoli open
respiratory system begins as a _____ off of the _____ located _____
begins as a diverticulum (lined w endoderm) / “lung bud”
off of the gut tube
between 4th & 6th pharyngeal arches
mesenchymal condensations around the laryngeal orifice gives rise to _____
epiglottis
thyroid cartilage
arytenoid cartilage
cricoid cartilage
_____ around the _____ gives rise to epiglottis, thyroid cartilage, arytenoid cartilage, cricoid cartilage
mesenchymal condensations
around the
laryngeal orifice
endoderm gives rise to _____
epithelium & glands
splanchnic (visceral) mesoderm gives rise to _____
stroma, cartilage, fibrous tissue
laryngotracheal diverticulum is separated from gut tube by _____; & then immediately the respiratory bud _____
tracheoesophageal septum
respiratory bud splits into 2 branches- (primary bronchi)
if something goes wrong w tracheoesophageal septum what happens, & most common form is what
tracheoesophageal fistulas
-abnormal connections between trachea & esophagus
esophageal atresia
-newborn immediately coughs up milk; regurg. enters lung
if lung bud doesn’t separate into 2 bronchi, two things can happen
agenesis (only one lung)
hypoplasia (two small lungs)
weeks for pseudoglandular period; & is fetus viable
6-16 weeks
fetus NOT viable
weeks for canalicular period; & is fetus viable
16-26 weeks
fetus only viable after 24 weeks
what fetus age is surfactant first produced
20 weeks
weeks for terminal sac period
26-birth
weeks for alveolar period
32 weeks - 8 years
_____ folding brings heart & septum transversum into thorax region
cephalocaudal folding
after cephalocaudal folding, part of heart is _____
anchored to anterior body wall via septum transversum
how is the diaphragm formed
-septum transversum fuses w pleuroperitoneal membrane (divides pleural & peritoneal cavities)
-muscles from body wall contributes to diaphragm as body grows
what happens if pleuroperitoneal canal doesn’t close
congenital diaphragmatic hernia
-intestines herniate into pleural cavity