airway resistance Flashcards

1
Q
A
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2
Q

what disease is work of breathing increased in

A

both restrictive and obstructive diseases

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3
Q

define work of breathing

A

energy used to inhale and exhale

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4
Q

equation for work or breathing

A

W = P x V

(pressure x volume)

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5
Q

% cost of O2 consumption during:

-quiet breathing at rest
-hyperventilation
-obstructive lung disease

A

5%
30%
very high

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6
Q

what holds an airway open

A

pressure difference across the airway (except during forced expiration)

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7
Q

dynamic compression of airways occurs when

A

during forced expiration

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8
Q

what is flow determined by during dynamic compression

A

alveolar pressure minus intrapleural pressure

(not armospheric pressure)

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9
Q

how does COPD exaggerate the dynamic compression of airways

A

increase in resistance of peripheral airways

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10
Q

how does emphysema exaggerate the dynamic compression of airways

A

reduced lung elastic recoil & loss of radial traction on airways

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11
Q

what is the location of the MOST airway resistance in the respiratory system

A

at the medium-sized bronchi

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12
Q

poiseuille’s law for resistance equation

A

R: resistance
n: viscosity
l: length
pi: 3.14
r: radius

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13
Q

reducing radius (r) by 50% will increase flow (R) by how much

A

16-fold

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