airway resistance Flashcards
what disease is work of breathing increased in
both restrictive and obstructive diseases
define work of breathing
energy used to inhale and exhale
equation for work or breathing
W = P x V
(pressure x volume)
% cost of O2 consumption during:
-quiet breathing at rest
-hyperventilation
-obstructive lung disease
5%
30%
very high
what holds an airway open
pressure difference across the airway (except during forced expiration)
dynamic compression of airways occurs when
during forced expiration
what is flow determined by during dynamic compression
alveolar pressure minus intrapleural pressure
(not armospheric pressure)
how does COPD exaggerate the dynamic compression of airways
increase in resistance of peripheral airways
how does emphysema exaggerate the dynamic compression of airways
reduced lung elastic recoil & loss of radial traction on airways
what is the location of the MOST airway resistance in the respiratory system
at the medium-sized bronchi
poiseuille’s law for resistance equation
R: resistance
n: viscosity
l: length
pi: 3.14
r: radius
reducing radius (r) by 50% will increase flow (R) by how much
16-fold