pulm disease restrictive lung disease Flashcards

1
Q

what is a restrictive lung disease

A

idiopathic pulmonary fibrosis

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2
Q

what is the most common feature in idiopathic pulm fib that leads to scarring, fibrosis, and cap obliteration

A

infiltration of the lung by inflammatory cells and fluid

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3
Q

progressive dry and persistent cough is indicative of

A

idiopathic pulm fibrosis

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4
Q

what are the major risk factors of IPF

A

smoking

- environment expsure to organic and inorganic dust

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5
Q

why is it important to ask about occupation when somebody comes in with a cough?

A

inhaling something at work that can lead to condition like IPF

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6
Q

fibrosis surrounding expanded small airspaces is seen as ____ on xrays

A

honeycombing; interstitial* pulm fibrosis

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7
Q

what are some reasons TB has reemerged*

A
  • those with HIV
  • bacterial resistance to medications
  • inc international travel and emigration from areas where TB is endemic
  • incr numbers in homeless ppl and drug abusers
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8
Q

what is the bacteria known as in TB?

A

mycobacterium tuberculosis (rod shaped acid fast bacilli)

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9
Q

how does TB spread*

A

via droplet transmission (airborne)

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10
Q

transmission of TB is influenced by (4 things)*

A
  • number of bacilli i the droplets
  • virulence of the bacilli
  • degree of ventilation,
  • occasions of aerosolization
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11
Q

where are the majority of bacilli trapped in?

A

upper parts of the airways where mucus secreting goblet cells exist

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12
Q

how does cilia of the cells work to prevent infection in most ppl with TB?

A

they beat the mucus and its entrapped particles up for removal

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13
Q

if the bacili in the droplets bypass the mucociliary system, phagocytosis by macrophages occurs which leads to what 2 types of TB?*

A

Latent TB
or
Primary progressive tb

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14
Q

what can you find on a cxr on a pt positive for TB?

A

Ghon complex

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15
Q

what is the function of formation of granulomas around organisms?

A

further growth is restricted and latency develops

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16
Q

the necrotic environemnt resembling soft cheese is referred to as ____ and it is formed within ____ weeks

A

caseous necrosis; 2-3

17
Q

a pt with a weak immune system infected by TB will develop which type of TB?

A

primary progressive TB

18
Q

what does necrotic tissue undergo that leads to a fibrous wall losing its structure in primary progressive tb

A

liquefaction

19
Q

in latent pts wuth TB have caseous vs in immunocompromised pts with primary progressive tb their lungs show

A

cavitation (air filled cavity at site)– look like holes

20
Q

when tb spreads to blood vessels is known as

A

extrapulmonary TB

21
Q

tb bacilli can drain in what locations?

A

lymphatic system –> tracheobronchial lymph nodes

  • Blood stream
  • lymphatics
  • pleura
  • bones/joints (potss disease
  • meninges (cns)
22
Q

are pts with latent TB infectious? can symtptoms develop?

A

negativo for both

- stays dormant forever and ever