other cardio diseases Flashcards

1
Q

most common problem in coronary artery disease CAD

A

atherosclerosis

-sob, diaphoresis, n/v

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2
Q

pt taking cocaine and low supply/deman of O2 –> signifies

A

CAD

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3
Q

explain process in atherosclerosis

A

1) plt aggregates
2) smooth muscle cells migrate to intima and multiply
3) endothelial cells regenerate to recover (thickening)
4) plaque (thrombi)
5) rupture –> lead to MI

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4
Q

thromboxane A2, serotonin and endolial dysfxn can all cause a ___ in blood flow seen in _____ disease

A

decrease

-CAD

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5
Q

“stunned” myocardiyn

A

restorations after LONG periods of ischemia

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6
Q

persisting period of CP can lead to

A

IM

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7
Q

pt severe cp worse with inspiration is significant of

A

Pericarditis

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8
Q

to and fro rub with high pitch is indicative of

A

pericarditis

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9
Q

kussmal sign

A

increase of JVP with inspiration RAP too

*Pericarditis

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10
Q

calcium can lead to

A

scarring

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11
Q

diastolic knock

A

filling is normal but suddenly stops due to the stiffness in pericarditis
-makes v wave noticeable

seen in pericarditis

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12
Q

becks triad and where is it seen

A

-hypotension
-elevated JVP
-muffled heart sounds
——————
Pericardial Effusion and Tamponade

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13
Q

arteriole is to _____ pressure as venue is to _____ pressure seen in capillary occlusion

A

1) hydrostatic

2) oncotic

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14
Q

what is the most potent vasoconstrictor

A

endothelia-L1

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15
Q

most potent vasodilator

A

NOS

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16
Q

diff b/w BNP and ANP

A

bnp is in ventricles, and ANP is in atrium myocyte stretch

17
Q

vasodilator vs vasoconstriction

  • prostacyclin
  • thromboxane
  • NO
  • endothelin
  • norepi +epi
  • kinins
  • Natriuretics
A

vasoconstrictors:
thromboxane, endothelia, norepi + epi,

Vasodilators:
prostacyclin, NO, kinins, natriuretics,

18
Q

c-reactive protein is a marker of

A

inflammation or plaques

19
Q

oxidized LDLs inhibit

A

NO

20
Q

chylomicron

A

protein coat of lipids

21
Q

estrogen can remove ___ but also ___ blood clots

A

cholesterol; increase

22
Q

homocysteine is seen in ____ and metabolized enzymes dependent on these 4 supplements

A

atherosclerosis ; B6, B12, folic acid

23
Q

what is and where is homans syndrome is seen in

A

calf pain at dorsiflexion of foot; DVT

24
Q

4 types of shock

A

hypovolumic
distributive
cardiogenic
obstructive

25
Q

Virchows triad

A

1) endothelial damage
2) Abnl blood flow
3) inc coag of blood
—–
seen in thrombosis/dvt

26
Q

canalization

A

new lumen form within the thrombus to make hole for blood to get through

in thrombosis

27
Q

left vs right sided embolization

A

left–> stroke out to the cerebral
right –> PE (coming from DVT to lungs)

thrombosis

28
Q

what’s affected in DVT

A

lower extremities and pelvis

29
Q

capacitance vs resistance vessels

A

resistance- arteries

capacitance- veins

30
Q

explain RAAS activation

A

angiotensin 2 stimulates aldosterone -> Na resorption and K excretion–> inc volume and BP

31
Q

two important cytokines

A

interleukins and tumor necrosis factor

-role in hyperr=trophy and apoptosis