PT/INR, APPT FOR HEPARIN and Coumadin Flashcards
What does PT stand for in the context of coagulation testing?
Prothrombin Time
What does INR stand for?
International Normalized Ratio
What is the primary purpose of measuring PT/INR?
To assess the blood’s ability to clot and monitor anticoagulation therapy.
True or False: A higher INR indicates a greater risk of bleeding.
True
What is the therapeutic range for INR in patients on Coumadin?
Typically between 2.0 and 3.0, depending on the indication.
What does aPTT stand for?
Activated Partial Thromboplastin Time
What is the primary use of aPTT testing?
To monitor patients on heparin therapy.
Fill in the blank: The normal range for aPTT is typically ______ seconds.
30 to 40
True or False: Heparin is monitored using PT/INR.
False
What lab value indicates that a patient is at risk for thrombosis while on Coumadin?
An INR below the therapeutic range.
What is the effect of Coumadin on the coagulation cascade?
It inhibits vitamin K-dependent clotting factors.
Multiple choice: Which of the following factors does Coumadin affect? A) Factor II B) Factor VII C) Factor IX D) All of the above
D) All of the above
What is the target INR for patients with atrial fibrillation on anticoagulation therapy?
2.0 to 3.0
Fill in the blank: The antidote for Coumadin is ______.
Vitamin K
True or False: aPTT is prolonged in patients taking Coumadin.
False
What is the significance of a high aPTT?
It indicates an increased risk of bleeding.
What conditions are commonly treated with Coumadin?
Atrial fibrillation, deep vein thrombosis, and pulmonary embolism.
What is a common side effect of heparin therapy?
Heparin-induced thrombocytopenia (HIT)
Fill in the blank: The typical therapeutic range for aPTT during heparin therapy is ______ seconds.
60 to 80
What lab test would you order to monitor a patient on low molecular weight heparin?
Anti-Xa levels (not routinely aPTT)
True or False: INR is used to monitor the effects of heparin.
False
What is the primary action of heparin?
To enhance the activity of antithrombin III.
What dietary consideration should patients on Coumadin be aware of?
Consistent intake of vitamin K-rich foods.
What is the risk associated with an INR greater than 4.0?
Increased risk of significant bleeding.
