Psychopathology Flashcards
Anxiety Disorders
triggered by both real and imagined things
Generalized Anxiety Disorder (GAD)
Panic Disorder
Generalized Anxiety Disorder
continuous worry about many things, 6+ months
Hypervigilance: over-attentive to threats
- overactive amygdala; less inhibition from prefrontal cortex
Panic Disorder
Recurrent, unpredictable, unprovoked panic with somatic symptoms (shortness of breath, sweating, palpitations)
1 month of debilitating worry
over-interpreting physiological arousal as catastrophic
Phobias
intense irrational fear that is specific to an object or situation
leads to avoidance
Obsessive Compulsive Disorder
Obsessions:
-disturbing intrusive thought
-fear is often only about a thought vs OCD fear is concrete
Compulsions:
-repetitive actions or ritual in response to obsession
-checking stove, cleaning, symmetry
Consume 1+ hr of da and interfere with relationships
safety/closure signal from frontal lobe does not reach limbic system and basal ganglia
Major Depressive Disorder
symptoms: prolonged sadness, absence of pleasure (anhedonia), hopelessness; worthlessness; excessive self-blame
physical symptoms: abnormal sleep, concentration, appetite; slowed boy movements
often concurrent with GAD, which often begins first
most severe: with psychosis (hallucinations, delusions, paranoia)
Serotonin and Norepinephrine deficiency theory is incomplete
Bipolar Disorder
manic depression
Mania: euphoria, high energy, less sleep, grandiose projects, impulsive behaviors
sometimes with psychosis: delusions and paranoia
Schizophrenia (what its not, positive & negative symptoms, difference from other illnesses, physiological basis
nothing to do with being of two minds/personalities
positive symptoms:
- disorganized thought, speech; loose associations
- Hallucinations, most often auditory
- Delusions- persecution, grandeur, being controlled, paranoia
- grossly disorganized or catatonic behavior
Negative symptoms:
- Anhedonia; flat effect; social isolation; less movement, speech, appetite
often lacks insight into psychopathology
1-2 year slow onset, starting with disorganization
too much neural pruning of gray matter in adolescent development
-Enlarged lateral ventricles
-neuronal loss in hippocampus and prefrontal cortex
-glutamate theory-bock glutamate receptor in normal people induces positive and negative symptoms
-dopamine theory = too little in prefrontal cortex, negative symptoms
= too much in basal ganglia, positive symptoms
neural pruning
the process by which extra neurons and synaptic connections are eliminated in order to increase the efficiency of neuronal transmissions.
PTSD
triggered by traumatic experience (vs. anxiety disorder)
re-experiencing
hyper-arousal
avoidance
Personality disorders
Clusters: A- odd paranoid schizoid sxhizotypal B- Dramatic anti-social borderline narcissistic histrionic C-Anxious obsessive compulsive avoidant dependent
Alzheimer’s Disease
progressive dementia
genes: overactive that produce beta-amyloid
brain plumbing- less clearance of plaque
Pathological 4DP
Distress Dysfunction Danger Deviance Pervasive over time and different situations
Biological factors
Neurotransmission
Genetics
Brain circuit function
Psychological Factors
content of consciousness matters to outcomes