Psychopathology Flashcards
Psychological Disorders
A syndrome marked by a clinically significant disturbance in an individual’s cognition, emotion regulation, or behavior.
Common Biological Themes
- Connectivity
- Oxidative stress in the brain
- Neurotransmitter imbalance
- Hyperactive amygdala responses
- Prefrontal cortex dysfunction
- Reward-circuitry dysfunction
Connectivity
- ASD
- MDD
- ADHD
- PTSD
- Alzheimer’s
Oxidative Stress in the Brain
- Inflammation
- Psychotic
- Anxiety
- Mood Disorders
Neurotransmitter Imbalance
- Mood Disorders
- OCD
Hyperactive Amygdala Responses
- Anxiety Disorders
- Mood Disorders
Prefrontal Cortex Dysfunction
- Schizophrenia
- PTSD
- MDD
- ADHD
Reward Circuitry Dysfunction
- Mesolimbic DA
- Liked to a TON of disorders
DSM-5
Diagnostic & Statistical Manual
- Entirely symptom based
RDoC
“Research Domain Criteria”
- Funded by NIMH
- The goal is to develop a sign-based classification of mental illness
Symptoms
Mostly patient-recorded, subjective
Signs
Objective measurements from diagnostic tests
Schizophrenia
- Affects 1% of the population
- Primary symptoms:
- Disorganized Thinking
- Hallucinations
- Delusions
Positive Symptoms of Schizophrenia
Things present in people with schizophrenia (that are not found in those without)
- Hallucinations
- Delusions
- Disorganized Thinking
Negative Symptoms of Schizophrenia
Features of normal cognition/behavior that are lost in people with schizophrenia
- Flat affect (emotional response)
- Impoverished thought & speech
