Neurotransmitters Flashcards
Amino Acids
Glutamate
GABA
Amines
Acetylcholine
Dopamine
Serotonin
Norepinephrine
Peptides
Endorphins
Glutamate
Important to memory, cognition, and mood regulation
SENT FROM: Everywhere!
SENT TO: Everywhere!
WHEN IT FUNCTIONS:
- Major excitatory neurotransmitter
- Critical to memory
WHEN IT MALFUNCTIONS:
- Oversupply may lead to migraines or even seizures
GABA
Slows down the brain
SENT FROM: Everywhere!
SENT TO: Everywhere!
WHEN IT FUNCTIONS:
- Major inhibitory neurotransmitter of the brain
WHEN IT MALFUNCTIONS:
- Undersupply linked to seizures, tremors, & insomnia
Alcohol acts on both GABA & Glutamate release
Acetylcholine
SENT FROM: Basal Forebrain
SENT TO: Cortex, amygdala, hippocampus, skeletal muscles, PNS
WHEN IT FUNCTIONS: CNS - learning & memory; PNS - motor control & parasympathetic activity
WHEN IT MALFUNCTIONS:
- Alzheimer’s disease occurs when Ach producing neurons deteriorate
Dopamine
Gives us feelings of pleasure, satisfaction, and motivation
SENT FROM: Midbrain - VTA & SN
SENT TO : Cortex, basal ganglia, & nucleus accumbens (reward area of the brain)
WHEN IT FUNCTIONS: influences movement, learning, reward, attention, and emotion
WHEN IT MALFUNCTIONS:
- Oversupply linked to schizophrenia
- Undersupply related to Parkinson’s
Serotonin
Aids in mood, sleep, digestion, nausea, wound healing, bone health, clotting, and libido
SENT FROM: Midbrain - Raphe Nuclei
SENT TO: Forebrain
WHEN IT FUNCTIONS: participates in mood, vision, sexual behavior, anxiety, hunger, sleep, & arousal
WHEN IT MALFUNCTIONS: undersupply linked to depression, affected by psychedelic drugs
SSRIs: Used to produce more serotonin; combat mood disorders
Norephinephrine
SENT FROM: Locus coeruleus & Lateral Tegmental Area (LTA)
SENT TO: Cortex, Limbic System, & Thalamic Nuclei
WHEN IT FUNCTIONS:
- Controls alertness, mood, & sexual behavior
WHEN IT MALFUNCTIONS:
- Undersupply can lead to depressed mood
Opioid Peptides
SENT FROM: Everywhere!
SENT TO: Everywhere, esp. Spinal Cords & PAG
WHEN IT FUNCTIONS:
- Influences perception of pain, thrill, sexual behavior, hunger, maternal care
WHEN IT MALFUNCTIONS:
- Oversupply via opiate drugs can suppress critical functions like breathing and heart rate.